Results 81 to 90 of about 24,362 (263)

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

open access: yesEpileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca   +10 more
wiley   +1 more source

Effect of antiepileptic drug comedication on lamotrigine concentrations [PDF]

open access: yes, 2018
AIM: To estimate the effect size of concomitant antiepileptic therapy on the concentrations of lamotrigine, a drug often prescribed in combination with other antiepileptic drugs (AED), which can act as enzyme inducers or inhibitors. ----- METHODS:
Klarica Domjanović, Iva   +9 more
core   +1 more source

Clinical utility and genetic landscape of exome sequencing in a large pediatric epilepsy cohort: Insights from a Turkish tertiary care center

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective To evaluate the diagnostic utility and genetic spectrum of next‐generation sequencing (NGS) in a large, well‐phenotyped cohort of Turkish pediatric patients with epilepsy of unknown etiology. Methods Between January 2021 and December 2024, 250 children (115 female, 135 male) with unexplained epilepsy underwent either whole‐exome ...
Derya Karaer   +4 more
wiley   +1 more source

Lamotrigine and severe skin eruptions

open access: yes, 2011
Lamotrigine is an important new addition to the drugs used to treat people with seizure disorders, but disconcerting are reports of a higher than expected incidence of severe skin reaction among children.
Cain, E. M.   +6 more
core   +1 more source

Lamotrigine ethanol monosolvate [PDF]

open access: yes, 2018
Lamotrigine is an active pharmaceutical ingredient used as a treatment for epilepsy and psychiatric disorders. Single crystals of an ethanolate solvate, C9H7Cl2N5·C2H5OH, were produced by slow evaporation of a saturated solution from anhydrous ethanol ...
Jason Potticary   +9 more
core   +1 more source

Lamotrigine Use in Pregnancy

open access: yes, 1999
Objective: To review the literature on the proposed mechanisms of teratogenicity of older antiepileptic drugs (AEDs) compared with lamotrigine. Data Sources: Published articles on the use of AEDs during pregnancy were identified from a comprehensive ...
Carol L Lilly, Barbara Kaplan-Machlis
core   +1 more source

Acute neural effects of the mood stabiliser lamotrigine on emotional processing in healthy volunteers: a randomised control trial

open access: yesTranslational Psychiatry
Lamotrigine is an effective mood stabiliser, largely used for the management and prevention of depression in bipolar disorder. The neuropsychological mechanisms by which lamotrigine acts to relieve symptoms as well as its neural effects on emotional ...
Marieke A. G. Martens   +5 more
doaj   +1 more source

Severe lamotrigine toxicosis in a dog

open access: yes, 2017
Danielle Sawyer, Kathryn Gates Emergency and Critical Care Department, Advanced Critical Care and Emergency Specialty Services, Culver City, CA, USA Objective: The objective of this study was to describe a case of severe lamotrigine toxicosis in a dog ...
Gates K, Sawyer D
core  

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

open access: yesEpileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus   +6 more
wiley   +1 more source

Collaboration in pharmacovigilance: lamotrigine and fatal severe cutaneous adverse reactions – a review of spontaneous reports

open access: yes, 2017
Neil Brickel,1 Haris Shaikh,1 Andrew Kirkham,2 Greg Davies,1 Michelle Chalker,1 Pascal Yoshida3 1Global Clinical Safety and Pharmacovigilance, GlaxoSmithKline, Uxbridge, Middlesex, UK; 2Classic and Established Products, GlaxoSmithKline, Brentford ...
Kirkham A   +5 more
core  

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