Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS [PDF]
Despite significant progress in the development of therapies for relapsing MS, progressive MS remains comparatively disappointing. Our objective, in this paper, is to review the current challenges in developing therapies for progressive MS and identify ...
Baker, D +17 more
core +2 more sources
Seizure outcome after switching antiepileptic drugs: A matched, prospective study. [PDF]
OBJECTIVE: Outcomes after changing antiepileptic drugs (AEDs) have largely been studied in single cohort series. We recently reported the first study to examine this question in a controlled manner.
Finamore, Jon Marc +5 more
core +2 more sources
Background: The two antiepileptic drugs lacosamide and lamotrigine exert their antiepileptic effect by inhibiting sodium channels. Lacosamide enhances the inactivation of sodium channels, while lamotrigine inhibits the activation of the channel ...
Julian Wolfes +6 more
doaj +1 more source
Eating and feeding disorders in pediatric age [PDF]
Eating and feeding disorders are common in pediatric age and may be important to discover and recover the early symptoms in order to optimize the treatment and ...
Cerroni F. +20 more
core +1 more source
Failure of Ketamine Anesthesia in a Patient with Lamotrigine Overdose
Introduction. It is important to know which clinical situations prevent ketamine from working. Case Report. We present the case of the psychiatric inpatient who was admitted to our emergency department after ingesting a toxic dose of lamotrigine, unknown
Daniel Kornhall, Erik Waage Nielsen
doaj +1 more source
Efficacy of Lamotrigin in Treatment of Avoidance / Numbing in Post-traumatic Stress Disorders
: Introduction & Objective: Post-traumatic stress disorder (PTSD) is a chronic illness which is difficult to treat yet, it is a common disorder which is associated with significant morbidity and mortality. The hypothesis that exposure to traumatic events
S Amanat, H Afshar
doaj
Effects of adjunctive eslicarbazepine acetate on serum lipids in patients with partial-onset seizures: Impact of concomitant statins and enzyme-inducing antiepileptic drugs. [PDF]
PURPOSE: To evaluate the effects of eslicarbazepine acetate (ESL) on lipid metabolism and to determine whether reduced statin exposure during ESL therapy has clinical consequences. SUBJECTS AND METHODS: We conducted a post-hoc analysis of pooled data for
Ben-Menachem, Elinor +11 more
core +1 more source
A randomized, double-blind, placebo controlled, multi-center, phase III clinical trial to evaluate the efficacy of lamotrigine in the management of chemotherapy induced peripheral neuropathy [PDF]
Σημείωση: διατίθεται συμπληρωματικό υλικό σε ξεχωριστό ...
Τσιμπούρα, Παρασκευή
core +1 more source
Older individuals may be more susceptible to cognitive side effects of antiepileptic drugs than are younger adults. This randomized, double-blind study compared the cognitive effects of lamotrigine (median maintenance dosage, 500.0 mg/d) and topiramate ...
Steve S. Chung +3 more
doaj +1 more source

