Results 51 to 60 of about 1,438,311 (284)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Landscape Architectural Design as Scientific Inquiry? [PDF]
, 2011 This presentation discusses ‘landscape architectural design as scientific inquiry’ and exemplifies this with the description of a design process within climate-responsive design leading to new design knowledge.
Lenzholzer, S.
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Urban ScienceThe capacity for urban innovation is a significant symbol of contemporary urban development. In order to promote sustainable urban innovation, it is crucial to match and optimize innovation spaces, actors, and their behavioral needs.
Luhui Qi +5 more
doaj +1 more source
Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ, 2019 The field experiment was conducted during the agricultural season 2016-2017 in one of the greenhouses belonging to the Directorate of Agriculture of Basrah in Khor Al-Zubair, in order to study the effect of the bio-stimulator Amalgerol in some growth ...
Abdul Basset M. Al-Mahdi +2 more
doaj +1 more source
Plant material booklet 1: palms of Malaysia [PDF]
, 2001 This book is intended as quick reference for landscape architects, architects and urban planners in identifying palms for landscape planning and design of open spaces, recreational areas, residential landscape and street planting.
Abdul Rashid, Shahrulizam, Said, Ismail
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cultural elements’ influence on visual preferences in urban waterfronts’ walkways in Malaysia
Frontiers in Built EnvironmentWith the rapid urbanization in Malaysia, human activities have caused damage to many waterfront areas. Efforts are being made to restore the connection between the community and river waterfronts while creating attractive urban spaces.
Tun Liu +5 more
doaj +1 more source