Results 51 to 60 of about 305,128 (260)
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cost-Benefit Analysis of Urban Green Infrastructures: A Case Study of the LiuChuan River Corridor, Taichung City, from Linsenliu Bridge to Minquanliu Bridge [PDF]
Green infrastructure has been shown to play the role of adaptation and adjustment under the effect of harsh climate. The creation of urban green infrastructure is an important indicator of sustainable urban development, and determining the cost ...
Chao Jen-Chih, Lin Ji-Yuan
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
How Highway Landscape Visual Qualities Are Being Studied: A Systematic Literature Review
Highways play a vital role in the road transport system, connecting regions and cities in many parts of the world. It may sometimes offer scenic views or a visually appealing environment based on the availability of unique compositions of natural and man-
Hangyu Gao +5 more
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Landscape Design: Arranging Plants in the Landscape
In nature, plants grow in clusters and drifts, extending to overlap and interlock in layers as they merge with each other. In a planned landscape, use similar patterns to arrange plants, using layers and repetition. Learn more in this 4-page fact sheet written by Gail Hansen, and published by the UF Department of Environmental Horticulture, October ...
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The Theoretical Landscape of Service Design [PDF]
This conference paper discusses the theoretical landscape of service design. It will illustrate how service design is situated in a discourse on design research and outline the theoretical background of this multidisciplinary approach from a constructive and generative research perspective.
Piia Rytilahti +2 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

