Results 51 to 60 of about 301,865 (260)
Transactions of the Philosophical Society of Queensland(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Cost-Benefit Analysis of Urban Green Infrastructures: A Case Study of the LiuChuan River Corridor, Taichung City, from Linsenliu Bridge to Minquanliu Bridge [PDF]
E3S Web of ConferencesGreen infrastructure has been shown to play the role of adaptation and adjustment under the effect of harsh climate. The creation of urban green infrastructure is an important indicator of sustainable urban development, and determining the cost ...
Chao Jen-Chih, Lin Ji-Yuan
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Landscape Design: Arranging Plants in the Landscape
EDIS, 2011 In nature, plants grow in clusters and drifts, extending to overlap and interlock in layers as they merge with each other. In a planned landscape, use similar patterns to arrange plants, using layers and repetition. Learn more in this 4-page fact sheet written by Gail Hansen, and published by the UF Department of Environmental Horticulture, October ...
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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How Highway Landscape Visual Qualities Are Being Studied: A Systematic Literature Review
LandHighways play a vital role in the road transport system, connecting regions and cities in many parts of the world. It may sometimes offer scenic views or a visually appealing environment based on the availability of unique compositions of natural and man-
Hangyu Gao +5 more
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The Theoretical Landscape of Service Design [PDF]
, 2015 This conference paper discusses the theoretical landscape of service design. It will illustrate how service design is situated in a discourse on design research and outline the theoretical background of this multidisciplinary approach from a constructive and generative research perspective.
Piia Rytilahti +2 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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