Results 121 to 130 of about 942,623 (281)

Climate‐Driven Topographic Asymmetry Enhanced by Glaciers: Implications for Drainage Reorganization in Glacial Landscapes

open access: yesGeophysical Research Letters
Climate contrasts across drainage divides, such as orographic precipitation, are ubiquitous in mountain ranges, and as a result, mountain topography is often asymmetric.
Jingtao Lai, Kimberly Huppert
doaj   +1 more source

Free-energy landscape of nucleation with an intermediate metastable phase studied using capillarity approximation

open access: yes, 2011
Capillarity approximation is used to study the free-energy landscape of nucleation when an intermediate metastable phase exists. The critical nucleus that corresponds to the saddle point of the free-energy landscape as well as the whole free-energy ...
Johnson W. A.   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Multi‐Century Erosion and Landscape Evolution of Ephemeral Catchments in Response to Sub‐Daily Rainfall Distribution Changes

open access: yesGeophysical Research Letters
Changes in the properties of rainfall distributions at sub‐daily scales are key to assessing soil erosion rates under climate transition. However, such changes are difficult to detect and model, especially over landscape evolution timescales.
Yuval Shmilovitz   +2 more
doaj   +1 more source

Dating the landscape evolution around the Chauvet-Pont d'Arc cave. [PDF]

open access: yesSci Rep, 2021
Genuite K   +8 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

The Lasting Legacy of Megaflood Boulder Deposition in Mountain Rivers

open access: yesGeophysical Research Letters
Infrequent, large‐magnitude discharge (>106 m3/s) outburst floods—megafloods—can play a major role in landscape evolution. Prehistoric glacial lake outburst megafloods transported and deposited large boulders (≥4 m), yet few studies consider their ...
S. M. Morey   +5 more
doaj   +1 more source

Author Correction: Dating the landscape evolution around the Chauvet-Pont d'Arc cave. [PDF]

open access: yesSci Rep, 2021
Genuite K   +8 more
europepmc   +1 more source

Effects of neutral selection on the evolution of molecular species

open access: yes, 1997
We introduce a new model of evolution on a fitness landscape possessing a tunable degree of neutrality. The model allows us to study the general properties of molecular species undergoing neutral evolution.
Engelhardt, Robin, Newman, M. E. J.
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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