Results 101 to 110 of about 952,563 (300)

Evolution on a Rugged Landscape:Pinning and Aging

, 1997
Population dynamics on a rugged landscape is studied analytically and numerically within a simple discrete model for evolution of N individuals in one-dimensional fitness space.
D. Kessler, G. Blatter, I. Aranson, I. S. Novella, L. D. Landau, L. Tsimring, L. Tsimring, M. Alba, M. Eigen, P. Le Doussal, P. Sibani, S. Kaufmann, S. S. Plotkin, T. B. Kepler, V. M. Vinokur, V. Vinokur, W. Fontana, Y. G. Sinai   +17 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Continuity in morphological disparity in tropical reef fishes across evolutionary scales

Communications Biology
Tropical reef fishes exhibit a large disparity of organismal morphologies contributing to their astonishing biodiversity. Morphological disparity, scaling from differences among individuals within populations to differences among species, is governed by ...
Giulia Francesca Azzurra Donati, Camille Albouy, Thomas Claverie, David Mouillot, Rodney Govinden, Oskar Hagen, Shameel Ibrahim, Julius Pagu, Irthisham Zareer, Fabien Leprieur, Loïc Pellissier   +10 more
doaj   +1 more source

Geoarchaeology and PalaeoDEMs Modelling to Assess the Archaeological Potential of Ravenna and Its Hinterland

Journal of Open Archaeology Data
This paper presents a collection of nine datasets developed as part of a PhD research project in Archaeology to investigate landscape transformations in the hinterland of Ravenna.
Michele Abballe
doaj   +1 more source

Eigen model as a quantum spin chain: exact dynamics

, 2004
We map Eigen model of biological evolution [Naturwissenschaften {\bf 58}, 465 (1971)] into a one-dimensional quantum spin model with non-Hermitean Hamiltonian. Based on such a connection, we derive exact relaxation periods for the Eigen model to approach
C. Kamp, C.O. Wilke, Chin-Kun Hu, David Saakian, E. Baake, I. Leuthausser, L. Franz, M. Eigen, M. Eigen, M. Snoad, P. Schuster, P. Tarazona, T. Ohta, Y.Y. Goldschmidt   +13 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Geographic Patterns of Intra‐ and Interspecific Diversity of Riverine Fish Species in the Italian Northern Apennines and Ligurian Alps

Ecology and Evolution
Understanding the intricate dynamics of biodiversity within and across riverine ecosystems, influenced by geological history and environmental factors, is crucial for effective conservation and management strategies.
Dominik Kirschner, Gabrielle Vance, Virginie Marques, Monika Goralczyk, Alice Valentini, Xiaowei Zhang, Sean D. Willett, Florian Altermatt, Loïc Pellissier   +8 more
doaj   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Regional uniqueness of tree species composition and response to forest loss and climate change

Nature Communications
The conservation and restoration of forest ecosystems require detailed knowledge of the native plant compositions. Here, we map global forest tree composition and assess the impacts of historical forest cover loss and climate change on trees.
Nina van Tiel, Fabian Fopp, Philipp Brun, Johan van den Hoogen, Dirk Nikolaus Karger, Cecilia M. Casadei, Lisha Lyu, Devis Tuia, Niklaus E. Zimmermann, Thomas W. Crowther, Loïc Pellissier   +10 more
doaj   +1 more source

The ground beneath our feet: A critical reflection on 135 years of landscape evolution models for southern Africa

South African Journal of Science
In his 1925 paper describing the Taung Child fossil, Dart makes various assertions about the landscape around Taung, inferring past climate dynamics, and the role these factors play in the evolution of our early prehuman relatives.
Rivoningo Khosa, Vela Mbele, Kelly Kirsten, Robyn Pickering   +3 more
doaj   +1 more source