Results 91 to 100 of about 188,104 (310)

Neotectonics, flooding patterns and landscape evolution in southern Amazonia [PDF]

open access: yes, 2014
The paper examines the role of neotectonic activity in the evolution of the landscape in southern Amazonia during the Holocene. It uses both new and published data based on the analysis of remote sensing imagery and extensive field work in the Llanos de ...
Lombardo, Umberto   +1 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Analysis of the fitness landscape for the class of combinatorial optimisation problems [PDF]

open access: yes, 2013
Anatomy of the fitness landscape for a group of well known combinatorial optimisation problems is studied in this research and the similarities and the differences between their landscapes are pointed out.
Tayarani-Najaran, M.-H.
core  

Quantitative Modeling of Landscape Evolution [PDF]

open access: yes, 2013
This chapter reviews quantitative modeling of landscape evolution – which means that not just model studies but also modeling concepts are discussed. Quantitative modeling is contrasted with conceptual or physical modeling, and four categories of model ...
Claessens, L   +3 more
core   +3 more sources

Three‐Dimensional Modeling of the Coevolution of Landscape and Soil Organic Carbon

open access: yesWater Resources Research, 2019
Soil organic carbon (SOC) is going through rapid reorganization due to anthropogenic influences. Understanding how biogeochemical transformation and erosion‐induced SOC redistribution influence SOC profiles and stocks is critical to our food security and
Qina Yan   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Landscape genetics of highly disturbed arable systems : insights gained from investigating a small mammal species [PDF]

open access: yes, 2015
A large proportion of the earth’s surface is dedicated to food production, and agriculture is widely acknowledged to influence local biodiversity via habitat loss and degradation.
Wilson, Amanda
core  

A Confidence Scoring Procedure for eDNA Metabarcoding Records and Its Application to a Global Marine Fish Dataset

open access: yesEnvironmental DNA
Environmental DNA (eDNA) metabarcoding is changing the way biodiversity is surveyed in many types of ecosystems. eDNA surveys are now commonly performed and integrated into biodiversity monitoring programs and public databases.
Andrea Polanco F.   +8 more
doaj   +1 more source

MOLECULAR EVOLUTION OVER THE MUTATIONAL LANDSCAPE [PDF]

open access: yesEvolution, 1984
A common observation in phylogenetic comparisons of the amino acid sequences of a particular protein is that the rate of evolution of the protein is nearly constant over extended periods of time. This constancy was first noticed by Zuckerkandl and Pauling (1965) and prompted them to call the amino acid substitution process a "molecular evolutionary ...
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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