Results 121 to 130 of about 952,563 (300)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Landscape Evolution and It's Impact of Ecosystem Service Value of the Wuhan City, China. [PDF]
Int J Environ Res Public Health, 2021 Chen R, Huang C.
europepmc +1 more source
Hierarchical Crossover and Probability Landscapes of Genetic Operators
, 1995 The time evolution of a simple model for crossover is discussed. A variant of this model with an improved exploration behavior in phase space is derived as a subset of standard one- and multi-point crossover operations.
Bornholdt, Stefan, Schuster, Heinz Georg
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Geophysical Research LettersClimate contrasts across drainage divides, such as orographic precipitation, are ubiquitous in mountain ranges, and as a result, mountain topography is often asymmetric.
Jingtao Lai, Kimberly Huppert
doaj +1 more source
Dating the landscape evolution around the Chauvet-Pont d'Arc cave. [PDF]
Sci Rep, 2021 Genuite K +8 more
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Geophysical Research LettersChanges in the properties of rainfall distributions at sub‐daily scales are key to assessing soil erosion rates under climate transition. However, such changes are difficult to detect and model, especially over landscape evolution timescales.
Yuval Shmilovitz +2 more
doaj +1 more source
Author Correction: Dating the landscape evolution around the Chauvet-Pont d'Arc cave. [PDF]
Sci Rep, 2021 Genuite K +8 more
europepmc +1 more source