Results 131 to 140 of about 942,623 (281)
Evolution of regulatory landscapes
, 2018 Trabajo presentado en el Worshop UNIA "Chromosome architecture and topological stress" celebrado en Baeza (España) del 08 al 10 de octubre de 2018.
openaire +9 more sources
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Structure and diversity of dung beetles communities (Coleoptera: Scarabaeoidea) in southern Larzac (France) [PDF]
, 2008 Introduction: The ecosystems of Southern Larzac (France) have experienced an evolution of pastoral practices which progressively led to a change of landscape structure.
Deguine, Jean-Philippe +2 more
core
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Landscape Evolution and Simulation of Rural Settlements around Wetland Park Based on MCCA Model and Landscape Theory: A Case Study of Chaohu Peninsula, China. [PDF]
Int J Environ Res Public Health, 2021 Fan X +10 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Forms of Emergence and the Evolution of Economic Landscapes [PDF]
Over the past two decades, the notion of ÔemergenceÕ has attracted increasing attention and controversy across the social sciences, as par of a growing interest in the applicability of complexity theory to socio-economic-political systems.
Peter Sunley, Ron Martin
core
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source