Results 81 to 90 of about 942,623 (281)
Environmental DNAEnvironmental DNA (eDNA) metabarcoding is changing the way biodiversity is surveyed in many types of ecosystems. eDNA surveys are now commonly performed and integrated into biodiversity monitoring programs and public databases.
Andrea Polanco F. +8 more
doaj +1 more source
Kovacs effects in an aging molecular liquid
, 2003 We study by means of molecular dynamics simulations the aging behavior of a molecular model of ortho-terphenyl. We find evidence of a a non-monotonic evolution of the volume during an isothermal-isobaric equilibration process, a phenomenon known in ...
A. J. Kovacs +7 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Labyrinthic granular landscapes
, 2001 We have numerically studied a model of granular landscape eroded by wind. We show the appearance of labyrinthic patterns when the wind orientation turns by $90^\circ$. The occurence of such structures are discussed. Morever, we introduce the density $n_k$
D. Goossens +7 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
THE CONDITIONING FEATURES OF DITCHES PROCESSES AT THE SEDIMENTARY STRUCTURES OF THE PERIPHERAL DEPRESSION IN RIO GRANDE DO SUL [PDF]
Sociedade & Natureza, 2005 Aiming to define the conditioning features responsible for the different erosionprocesses actuating at the drain heads between Jacuí and Ibicuí rivers - at PeripheralDepression in Rio Grande do Sul, we analysed the geologic/geomorphologic aspects ...
Ivaniza de Lourdes Lazzarotto Cabral +3 more
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The evolution of landscapes [PDF]
Nature, 1982 Climatic Geomorphology. By Julius Budel. Pp.528. Hbk ISBN 0-691-08294-4; pbk ISBN 0-691-08295-2. (Princeton University Press: 1982.) Hbk £40.62, $65; pbk £15.31, $24.50.
openaire +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source