Results 71 to 80 of about 5,474,771 (289)

Electric Bicycle Lane-Changing Behavior under Strategy Games

open access: yes, 2018
The random lane-changing behavior of electric bicycles brings a great safety hazard to urban transportation: According to the national traffic accident statistics in 2015, 8.22% of traffic accidents are caused by non-motor vehicle violations. Among them,
Sitian Chen   +3 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Lane-by-Lane Analysis of Crash Occurrence Based on Driver's Lane-Changing and Car-Following Behavior

open access: yes, 2011
This study investigates the effects of the traffic flow parameters related to individual drivers\u27 lane-changing and car-following behavior on the occurrence of sideswipe and rear-end crashes on freeways.
Peter Y. Park   +5 more
core   +1 more source

Optimization of lane-changing distribution for a motorway weaving segment [PDF]

open access: yes, 2017
Article free to read on journal website\ud \ud The traffic in a weaving segment is subject to lane-changing turbulence in excess of that normally present on basic motorway segments.
Nasser R. Sabar   +7 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Effect model of urban traffic congestion on driver’s lane-changing behavior

open access: yesAdvances in Mechanical Engineering, 2017
Road traffic congestion has become a normal state and caused many problems in large cities of China, and lane-changing model has attracted increased attention in recent years.
Weiwei Qi   +3 more
doaj   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

open access: yesArthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler   +20 more
wiley   +1 more source

A COMPREHENSIVE BEHAVIORAL STUDY ON LANE CHANGING MANUEVERS [PDF]

open access: yes, 2019
Since changing lanes might cause traffic congestion and car crashes, the investigation on different aspects of this behavior remains critical.
Ramezanpour Nargesi, Saeed Reza
core   +1 more source

A lane-changing behavioral preferences learning agent with its applications

open access: yesComputer Science and Information Systems, 2015
Traditional lane-changing (LC) behavioral researches usually focus on the driver?s cognitive performance which includes the driver?s psychological and behavioral habit characteristics, rarely involving the affection of expert driver?s comprehensive behavioral preferences, such as: safety and comfort performance in LC process.
Jian Wang 0022   +3 more
openaire   +2 more sources

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy