Results 71 to 80 of about 252,737 (261)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

LC-LLM: Explainable lane-change intention and trajectory predictions with Large Language Models

open access: yesCommunications in Transportation Research
To ensure safe driving in dynamic environments, autonomous vehicles should possess the capability to accurately predict lane change intentions of surrounding vehicles in advance and forecast their future trajectories.
Mingxing Peng   +6 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

A Graph-Based Method for Tactical Planning of Lane-Level Driving Tasks in the Outlook Region

open access: yesApplied Sciences
Road traffic regulations usually require that a vehicle can only move one lane during one lane change and must turn on the turn signal before changing lanes.
Qiang Zhang, Hsin Guan
doaj   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

open access: yesAdvanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin   +4 more
wiley   +1 more source

Fuzzy Logic-Based Autonomous Lane Changing Strategy for Intelligent Internet of Vehicles: A Trajectory Planning Approach

open access: yesWorld Electric Vehicle Journal
The autonomous lane change maneuver is a critical component in the advancement of intelligent transportation systems (ITS). To enhance safety and efficiency in dynamic traffic environments, this study introduces a novel autonomous lane change strategy ...
Chao He   +5 more
doaj   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian   +5 more
wiley   +1 more source

Current status of lane change intention recognition for autonomous vehicles

open access: yes工程科学学报
In recent years, with the rapid development of big data and artificial intelligence technology, data-driven automatic driving vehicle lane change intention recognition has become an active research area in the transportation field.
Huazhen FANG   +4 more
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

Empirical Approach for Determining Lane Change Distance at Obstacle Avoidance Manoeuvre

open access: yesPromet (Zagreb), 2016
The lane change of vehicles for avoiding hitting a sudden obstacle represents a significant and unique problem for traffic accident experts. Most mathematic models for determining the lane change distance are based on theoretical research studies and a ...
Zoran Miladin Papić   +3 more
doaj   +1 more source

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