Results 61 to 70 of about 270,632 (283)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Detection of Driver Styles in Lane Changes using Wavelet Transform [PDF]

Journal of Universal Computer Science
Lane change detection is crucial for intelligent transportation systems, as it affects traffic flow on both macroscopic and microscopic levels. Lane change models are widely used in traffic and transportation studies, making it important to understand ...
Yunus Emre Avcı, Adem Tuncer
doaj   +3 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Neal Lane Memorandum for Vice President Gore

, 2000
A memorandum for Vice President Gore from Neal Lane, Director of the Office of Science and Technology Policy (OSTP). Lane advises Vice President Gore on the recent release of the National Climate Change Assessment by the U.S.
Lane, Neal F.
core   +1 more source

2D-Action Asynchronous Cooperative Lane Change Trajectory Planning Method for Connected and Automated Vehicles

Journal of Advanced Transportation
The ability to change lanes safely, efficiently, and comfortably is an important prerequisite for the application of Connected-Automated Vehicles (CAVs).
Liyang Wei, Weihua Zhang, Haijian Bai, Jingyu Li   +3 more
doaj   +1 more source

Analysis of Highway Vehicle Lane Change Duration Based on Survival Model

Big Data and Cognitive Computing
To investigate highway vehicle lane-changing behavior, we utilized the publicly available naturalistic driving dataset, HighD, to extract the movement data of vehicles involved in lane changes and their proximate counterparts.
Sheng Zhao, Shengwen Huang, Huiying Wen, Weiming Liu   +3 more
doaj   +1 more source

Target Vehicle Selection Algorithm for Adaptive Cruise Control Based on Lane-changing Intention of Preceding Vehicle

Chinese Journal of Mechanical Engineering, 2021
To improve the ride comfort and safety of a traditional adaptive cruise control (ACC) system when the preceding vehicle changes lanes, it proposes a target vehicle selection algorithm based on the prediction of the lane-changing intention for the ...
Jun Yao, Guoying Chen, Zhenhai Gao
doaj   +1 more source

Bifurcation of Lane Change and Control on Highway for Tractor-Semitrailer under Rainy Weather [PDF]

, 2017
A new method is proposed for analyzing the nonlinear dynamics and stability in lane changes on highways for tractor-semitrailer under rainy weather. Unlike most of the literature associated with a simulated linear dynamic model for tractor-semitrailers ...
Guan, Z, Hongguo Xu, Kening Li, Li, K, Ronghui Zhang, Zhang, R, Zhiwei Guan, Jinsong Dong, Xu, H, Peng, T, Tao Peng, Dong, J   +11 more
core   +1 more source