Results 91 to 100 of about 10,558,900 (341)

Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis.

open access: yesBlood, 2013
Langerhans cell histiocytosis (LCH)-III tested risk-adjusted, intensified, longer treatment of multisystem LCH (MS-LCH), for which optimal therapy has been elusive.
H. Gadner   +14 more
semanticscholar   +1 more source

Primary Head and Neck Histiocytic Sarcoma of the Oropharyngeal Posterolateral Wall: A Case Report

open access: yesThe Laryngoscope, EarlyView.
Histiocytic sarcoma (HS) is a rare and aggressive malignancy, particularly uncommon in the head and neck region. This report describes the case of a 67‐year‐old male with HS originating from the oropharyngeal posterolateral wall, treated successfully with transoral CO2 laser excision and adjuvant proton radiotherapy.
Michael Dalè   +8 more
wiley   +1 more source

Skull Base Langerhans Cell Histiocytosis with Diabetes Insipidus and Panhypopituitarism- A Rare Clinical Entity

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2017
Introduction A case of Langerhans cell histiocytosis (LGH) involving extensive area of base of skull resulting in panhypopituitarism and diabetes insipidus (DI) is reported.
Anirban Ghosh   +2 more
doaj   +1 more source

Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net

open access: yesOrphanet Journal of Rare Diseases, 2013
Langerhans Cell Histiocytosis (LCH) is an orphan disease of clonal dendritic cells which may affect any organ of the body. Most of the knowledge about the diagnosis and therapy is based on pedriatic studies.
M. Girschikofsky   +15 more
semanticscholar   +1 more source

Stealth Drug Delivery of Mouse Serum Albumin‐Coated Paclitaxel‐Loaded Gelatin Nanoparticles for Targeted Cancer Therapy in Mice

open access: yesNano Select, EarlyView.
Our study presents a novel approach to localized cancer therapy by developing mouse serum albumin (MSA)‐coated paclitaxel (PTX)‐loaded gelatin nanoparticles (MSA@PTX‐loaded GNPs) as a stealth drug delivery system. Given the challenges of nanoparticle‐based chemotherapy, including rapid opsonization and limited drug accumulation at tumor sites, our work
Md. Annur Sadman   +10 more
wiley   +1 more source

Otic Langerhans' Cell Histiocytosis in an Adult: A Case Report and Review of the Literature

open access: yesCase Reports in Otolaryngology, 2013
Objective. To present a case of otic Langerhans' cell histiocytosis in an adult. Also included the diagnosis and management of the condition and a review of the relevant literature. Case Report.
Anil Gungadeen   +2 more
doaj   +1 more source

CD1a on Langerhans cells controls inflammatory skin diseases

open access: yesNature Immunology, 2016
CD1a is a lipid-presenting molecule that is abundantly expressed on Langerhans cells. However, the in vivo role of CD1a has remained unclear, principally because CD1a is lacking in mice.
Ji Hyung Kim   +11 more
semanticscholar   +1 more source

Vertical and temporal niche partitioning in Amazonian butterflies: implications for the evolution of thermal tolerance

open access: yesOikos, EarlyView.
Closely related species living in sympatry are often partitioned into divergent ecological niches. Such specialization can be enabled by the evolution of divergent traits enhancing adaptation to different niches. In this study, we investigate the partitioning of closely related butterfly species into different forest strata and daily activity time and ...
Titouan Bouinier   +2 more
wiley   +1 more source

Polyostotic Langerhans cell histiocytosis presenting as halitosis in a 24-year-old man: a case report

open access: yesJournal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare disease of the reticuloendothelial system. This report presents a novel case of Langerhans cell histiocytosis with systemic involvement that started with a simple chief complaint.
Hassan Mirmohammad Sadeghi   +6 more
doaj   +1 more source

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