Results 41 to 50 of about 10,554,839 (372)

The Cells of the Islets of Langerhans [PDF]

Journal of Clinical Medicine, 2018
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
openaire   +5 more sources

Neurodegenerative central nervous system disease as late sequelae of Langerhans cell histiocytosis. Report from the Japan LCH Study Group

Haematologica, 2008
Clinical features, brain magnetic resonance imaging findings and EDSS scores of 11 patients with neurodegenerative central nervous system Langerhans cell histiocytosis were analyzed in Japan.
Shinsaku Imashuku, Yoko Shioda, Ryoji Kobayashi, Gaku Hosoi, Hisanori Fujino, Shiro Seto, Hisashi Wakita, Akira Oka, Nagisa Okazaki, Naoto Fujita, Toshinori Minato, Kenichi Koike, Yukiko Tsunematsu, Akira Morimoto   +13 more
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Specific Protein Antigen Delivery to Human Langerhans Cells in Intact Skin

Frontiers in Immunology, 2021
Immune modulating therapies and vaccines are in high demand, not least to the recent global spread of SARS-CoV2. To achieve efficient activation of the immune system, professional antigen presenting cells have proven to be key coordinators of such ...
Mareike Rentzsch, Mareike Rentzsch, Robert Wawrzinek, Robert Wawrzinek, Claudia Zelle-Rieser, Helen Strandt, Lydia Bellmann, Felix F. Fuchsberger, Jessica Schulze, Jil Busmann, Juliane Rademacher, Stephan Sigl, Barbara Del Frari, Patrizia Stoitzner, Christoph Rademacher   +14 more
doaj   +1 more source

Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]

, 1984
Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
A.B. Steffens, Bernstein, Berthoud, Berthoud, Bloom, Bloom, Daniel, De Groot, De Jong, E.C. Lotter, F. Kuipers, Frohman, Frohman, G. Flik, Henquin, Inoue, Iversen, Iversen, Kaneto, Kaneto, Kaneto, Kaneto, Karam, Matsushita, McCaleb, Moltz, P.G.M. Luiten, Robertson, Shimazu, Shimazu, Shimazu, Steffens, Steffens, Strubbe, Strubbe, Strubbe   +35 more
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Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: evidence for hematopoietic plasticity

Haematologica, 2010
Background The hierarchical organization of hematopoiesis with unidirectional lineage determination has become a questionable tenet in view of the experimental evidence of reprogramming and transdifferentiation of lineage-determined cells.
Richard Ratei, Michael Hummel, Ioannis Anagnostopoulos, Doris Jähne, Renate Arnold, Bernd Dörken, Stephan Mathas, Thomas Benter, Oliver Dudeck, Wolf-Dieter Ludwig, Harald Stein   +10 more
doaj   +1 more source

The Origin of Langerhans Cells

Journal of Investigative Dermatology, 1980
Langerhans cells constitute a morphologically well-characterized subpopulation (3--8%) of mammalian epidermal cells and, in contrast to the bulk of epidermal cells, bear Fc-IgG and C3 receptors, express immune response associated (Ia) antigens, and function as antigen presenting cells and allogeneic stimulatory cells to primed T lymphocytes.
Kunihiko Tamaki, Stephen I. Katz, Georg Stingl   +2 more
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Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient [PDF]

Malaysian Orthopaedic Journal, 2011
Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations.
Mohd Ariff S, Joehaimey J, Ahmad Sabri O, Zulmi W   +3 more
doaj   +1 more source

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

, 2012
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X., Gaiser, M., Germain, R., Igyarto, B., Kaplan, D., Lämmermann, T., Tessarollo, L., Udey, a.   +7 more
core   +1 more source

A rare cause of recurrent spontaneous pneumothorax: Birt-hogg-dube syndrome [PDF]

, 2018
Birt-Hogg-Dube (BHD) syndrome is an unusual disorder characterized by the triad of cutaneous lesions, renal tumors and lung cysts. In cases with BHD syndrome, the frequency of recurrent pneumothorax is increased due to presence of multiple lung cysts. It
Demirci, M., Karaman, Engin, Ufuk, F., Yavaş, H.G.   +3 more
core   +1 more source

Langerhans cell histiocytosis of the maxillae in a child treated only with chemotherapy: a case report

Journal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics.
Angela Pia Cazzolla, Giuseppe Troiano, Khrystyna Zhurakivska, Eugenio Maiorano, Gianfranco Favia, Maria Grazia Lacaita, Giuseppe Marzo, Franca Dicuonzo, Stefano Andresciani, Lorenzo Lo Muzio   +9 more
doaj   +1 more source