Results 41 to 50 of about 10,482,646 (332)
A protective Langerhans cell–keratinocyte axis that is dysfunctional in photosensitivity
Langerhans cells limit ultraviolet radiation–induced keratinocyte apoptosis and skin injury, and this axis is dysfunctional in lupus photosensitivity. Abrogating keratinocyte apoptosis in lupus Lupus patients can experience photosensitivity as manifested
W. Shipman+18 more
semanticscholar +1 more source
Objective: Langerhans cell histiocytosis is an unusual disorder of unknown etiology with heterogeneous clinical behaviors and variable outcomes. It can involve one or more organs or systems, but to our best knowledge, parotid glands involvement in ...
Xiaojun Yuan+4 more
doaj +1 more source
Clinical features, brain magnetic resonance imaging findings and EDSS scores of 11 patients with neurodegenerative central nervous system Langerhans cell histiocytosis were analyzed in Japan.
Shinsaku Imashuku+13 more
doaj +1 more source
The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita+6 more
core +1 more source
The Cells of the Islets of Langerhans [PDF]
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
openaire +5 more sources
Background The hierarchical organization of hematopoiesis with unidirectional lineage determination has become a questionable tenet in view of the experimental evidence of reprogramming and transdifferentiation of lineage-determined cells.
Richard Ratei+10 more
doaj +1 more source
Background Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics.
Angela Pia Cazzolla+9 more
doaj +1 more source
Langerhans cell histiocytosis is a rare proliferative disease of histiocyte-like cells, the peak incidence of which occurs in early childhood. Pulmonary Langerhans Cell Histiocytosis is one of the forms of this disease, but it usually affects young ...
Victor V. Fomin+4 more
doaj +1 more source
Interleukin-12 p40 secretion by cutaneous CD11c(+) and F4/80(+) cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni [PDF]
Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson, S+3 more
core +2 more sources
The Origin of Langerhans Cells
Langerhans cells constitute a morphologically well-characterized subpopulation (3--8%) of mammalian epidermal cells and, in contrast to the bulk of epidermal cells, bear Fc-IgG and C3 receptors, express immune response associated (Ia) antigens, and function as antigen presenting cells and allogeneic stimulatory cells to primed T lymphocytes.
Kunihiko Tamaki+2 more
openaire +3 more sources