Results 41 to 50 of about 10,482,646 (332)

A protective Langerhans cell–keratinocyte axis that is dysfunctional in photosensitivity

open access: yesScience Translational Medicine, 2018
Langerhans cells limit ultraviolet radiation–induced keratinocyte apoptosis and skin injury, and this axis is dysfunctional in lupus photosensitivity. Abrogating keratinocyte apoptosis in lupus Lupus patients can experience photosensitivity as manifested
W. Shipman   +18 more
semanticscholar   +1 more source

Swelling of bilateral parotid glands: An unusual symptom of multisystem Langerhans cell histiocytosis

open access: yesSAGE Open Medical Case Reports, 2014
Objective: Langerhans cell histiocytosis is an unusual disorder of unknown etiology with heterogeneous clinical behaviors and variable outcomes. It can involve one or more organs or systems, but to our best knowledge, parotid glands involvement in ...
Xiaojun Yuan   +4 more
doaj   +1 more source

Neurodegenerative central nervous system disease as late sequelae of Langerhans cell histiocytosis. Report from the Japan LCH Study Group

open access: yesHaematologica, 2008
Clinical features, brain magnetic resonance imaging findings and EDSS scores of 11 patients with neurodegenerative central nervous system Langerhans cell histiocytosis were analyzed in Japan.
Shinsaku Imashuku   +13 more
doaj   +1 more source

The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]

open access: yes, 2015
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita   +6 more
core   +1 more source

The Cells of the Islets of Langerhans [PDF]

open access: yesJournal of Clinical Medicine, 2018
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
openaire   +5 more sources

Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: evidence for hematopoietic plasticity

open access: yesHaematologica, 2010
Background The hierarchical organization of hematopoiesis with unidirectional lineage determination has become a questionable tenet in view of the experimental evidence of reprogramming and transdifferentiation of lineage-determined cells.
Richard Ratei   +10 more
doaj   +1 more source

Langerhans cell histiocytosis of the maxillae in a child treated only with chemotherapy: a case report

open access: yesJournal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics.
Angela Pia Cazzolla   +9 more
doaj   +1 more source

Langerhans cell histiocytosis

open access: yesКлинический разбор в общей медицине, 2023
Langerhans cell histiocytosis is a rare proliferative disease of histiocyte-like cells, the peak incidence of which occurs in early childhood. Pulmonary Langerhans Cell Histiocytosis is one of the forms of this disease, but it usually affects young ...
Victor V. Fomin   +4 more
doaj   +1 more source

Interleukin-12 p40 secretion by cutaneous CD11c(+) and F4/80(+) cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni [PDF]

open access: yes, 2003
Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson, S   +3 more
core   +2 more sources

The Origin of Langerhans Cells

open access: yesJournal of Investigative Dermatology, 1980
Langerhans cells constitute a morphologically well-characterized subpopulation (3--8%) of mammalian epidermal cells and, in contrast to the bulk of epidermal cells, bear Fc-IgG and C3 receptors, express immune response associated (Ia) antigens, and function as antigen presenting cells and allogeneic stimulatory cells to primed T lymphocytes.
Kunihiko Tamaki   +2 more
openaire   +3 more sources

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