Results 81 to 90 of about 10,558,900 (341)

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Indeterminate cell histocytosis with naïve cells

Rare Tumors, 2013
Histiocytoses are a heterogeneous group of disorders characterized by proliferation and accumulation of cells of mononuclearmacrophage system and dendritic cells.
Sheren F Younes, Mona A Kandil, Rehab M Samaka, Ola A Bakry   +3 more
doaj   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Emerging Frontiers in Food Allergy Treatment: Progress, Challenges, and Prospects

Food Frontiers, EarlyView.
Food allergy is a rising global health concern with limited treatment options beyond allergen avoidance and emergency care. This review explores the evolving therapeutic landscape, highlighting advances in allergen immunotherapy, biologics such as monoclonal antibodies, and emerging vaccine‐based approaches.
Ayesha Zahid, Hazrat Ismail, Madiha Ajaz, Abdul Qadeer   +3 more
wiley   +1 more source

Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

Journal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects – by order of
Mohamad Jihad Mansour, Elias Mokbel, Eddy Fares, Janah Maddah, Fadi Nasr   +4 more
doaj   +1 more source

Incidence patterns and temporal trends of childhood cancer in Germany, 1980–2019: Forty years of childhood cancer registration in Germany

International Journal of Cancer, EarlyView.
What's New? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann, Maike Wellbrock, Claudia Trübenbach, Desiree Grabow, Martin Schrappe, Peter Kaatsch, Claudia Spix, Joachim Schüz, Cécile M. Ronckers   +8 more
wiley   +1 more source

Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion

Journal of Coloproctology, 2017
Langerhans’ cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells in the body. It affects mainly males, predominantly in childhood. Ulcerated plaques are one of the cutaneous forms of presentation.
Bruno Lorenzo Scolaro, Gustavo Becker Pereira, Daniel Cury Ogata, Fernanda Souto Padrón Figueiredo Vieira da Cunha, Ana Cristina Martins Effting, Rafael Oselame Guanabara   +5 more
doaj   +1 more source

Isolated gastrointestinal Langerhans cell histiocytosis in a 16‐month‐old child: A case report

JPGN Reports, EarlyView.
Abstract Langerhans cell histiocytosis (LCH) is a rare disorder characterized by clonal proliferation of Langerhans cells, most often involving the skin or bone. Isolated gastrointestinal (GI) involvement is extremely uncommon in young children. We report a 16‐month‐old girl with a 1‐month history of chronic vomiting, bloody diarrhea, and failure to ...
Al‐Qasim AL‐Bahlani, Laraib Touseeq, Mohammed Al‐Masqari, Emad Saad   +3 more
wiley   +1 more source

Langerhans cell histiocytosis

, 2013
Definition: A histiocytary proliferation of granuloma-like aspect with unknown etiology that may involve bone marrow, internal organs, skin, and mucosae.
openaire   +4 more sources