Results 81 to 90 of about 149,549 (315)

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. [PDF]

, 2015
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic and inflammatory microenvironment that is formed primarily by activated, myofibroblast-like, stellate cells.
Dhall, Deepti, Greene, Mark I, Morvaridi, Susan, Pandol, Stephen J, Wang, Qiang   +4 more
core   +1 more source

Comparison of the effects of metformin, citral, Cymbopogon citratus extract and silver nanoparticles of Cymbopogon citratus extract on oxidative stress indices and Nrf2 levels in experimental type 2 diabetes in rats

Animal Models and Experimental Medicine, EarlyView.
The experimental type 2 diabetes model in rats induced by streptozotocin and nicotinamide showed that silver nanoparticles synthesized from lemongrass extract modulate blood glucose, water and food intake, and enhance antioxidant enzyme synthesis and weight gains.
Milad Faraji, Mohammad Foad Noorbakhsh, Nasrin Kazemipour, Saeed Nazifi, Hamid Reza Moradi, Nasrollah Ahmadi, Maryam Azadmanesh   +6 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

MiR-23a Regulates Skin Langerhans Cell Phagocytosis and Inflammation-Induced Langerhans Cell Repopulation

Biology, 2023
Langerhans cells (LCs) are skin-resident macrophage that act similarly to dendritic cells for controlling adaptive immunity and immune tolerance in the skin, and they are key players in the development of numerous skin diseases.
Jie Wang, Nirmal Parajuli, Qiyan Wang, Namir Khalasawi, Hongmei Peng, Jun Zhang, Congcong Yin, Qing-Sheng Mi, Li Zhou   +8 more
doaj   +1 more source

Expansion of Regulatory T Cells in Patients with Langerhans Cell Histiocytosis [PDF]

, 2007
Frederic Geissmann and colleagues find that Langerhans cell accumulation in Langerhans cell histiocytosis results from survival rather than uncontrolled proliferation, and is associated with the expansion of regulatory T ...
Alain Fischer, Arico, Arico, Arielle Lellouch, Banchereau, Bank, Berhard Malissen, Bernard, Bernstrand, Betts, Boussiotis, Brabencova, Brigitte Senechal, Brousset, Chen, Christophe Glorion, da Costa, Dacic, Delabesse, Egeler, Emile, Eric Jeziorski, Favara, Feller, Francis Jaubert, Frederic Geissmann, Gaelle Elain, Geissmann, Geissmann, Geissmann, Gillitzer, Glotzbecker, Hage, Hawiger, Hori, Hosmalin, Jaffe, Jean Donadieu, Jean Francois Emile, Kaplan, Kawakubo, Kheira Beldjord, Klein, Ladisch, Laman, Lichtenstein, Liliane Boccon-Gibod, Loser, Mahnke, Marianne Debré, Michel Zerah, Misra, Mohammed Barkaoui, Murakami, Natacha Patey-Mariaud de Serre, Patrice Josset, Pierre Mary, Pouchot, Rolland, Roncarolo, Scholzen, Shimakage, Steinbrink, Steinman, Steinman, Tang, Virginie Grondin, Willman, Yagi, Yu, Yu   +70 more
core   +5 more sources

Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation

JEADV Clinical Practice, 2022
Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time.
Mar Ramírez‐Lluch, Isabel Colmenero, José Suárez, Saulo Carrión‐Marrero, Francisco Rodríguez‐Fuertes, Ana Mateos‐Mayo, Ángela Hernández‐Martín, Antonio Torrelo   +7 more
doaj   +1 more source

A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans [PDF]

, 2008
Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Burns, Christopher J., Jones, Peter M., Kitsou-Mylona, Isidora, Persaud, Shanta J., Squires, Paul E.   +4 more
core   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Are physiological oscillations physiological?

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Dynamics of cell-type transition mediated by epigenetic modifications [PDF]

arXiv, 2023
Maintaining tissue homeostasis requires appropriate regulation of stem cell differentiation. The Waddington landscape posits that gene circuits in a cell form a potential landscape of different cell types, wherein cells follow attractors of the probability landscape to develop into distinct cell types.
arxiv