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Allergy, 1989
The morphological, enzymatical, immunocytochemical and functional properties of Langerhans' cells are briefly reviewed. Langerhans' cells are located mainly in the squamous stratified epithelia, but are also present in the thymus and in superficial lymphnodes.
RUCO, Luigi+2 more
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The morphological, enzymatical, immunocytochemical and functional properties of Langerhans' cells are briefly reviewed. Langerhans' cells are located mainly in the squamous stratified epithelia, but are also present in the thymus and in superficial lymphnodes.
RUCO, Luigi+2 more
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Langerhans' cell histiocytosis cells are activated langerhans' cells
The Journal of Pathology, 1994AbstractLangerhans' cell histiocytosis (LCH) is characterized by the presence of large mononucleated cells, associated with inflammatory cells. The Langerhans' cell (LC) lineage of the mononucleated cells is suggested by the presence of Birbeck granules and the expression of CD1a.
M Leborgne+4 more
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Differentiation of Langerhans cells in Langerhans cell histiocytosis
Blood, 2001Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges from spontaneous resolution to a chronic and sometimes lethal disease. We studied 25 patients with various clinical forms of the disease.
Nicole Brousse+16 more
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Langerhans' cell histiocytosis
The Lancet, 2005A 38-year-old woman complained of persistent chest pain. A plain radiograph showed an irregularity on the sternum, and bone-scan showed uptake only in that area. Thoracic-abdominal CT showed an osteolytic lesion of the sternum (figure) without any other signs of neoplasia.
N. Fazio+4 more
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Journal of the American Academy of Dermatology, 1982
Langerhans cells (LCs) function as the most peripheral outpost of the immune system. Although first identified in the skin, these cells probably originate in the bone marrow and migrate actively between the epidermis and the lymph nodes. They appear to play a critical role in immune surveillance and the development of contact allergy. The importance of
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Langerhans cells (LCs) function as the most peripheral outpost of the immune system. Although first identified in the skin, these cells probably originate in the bone marrow and migrate actively between the epidermis and the lymph nodes. They appear to play a critical role in immune surveillance and the development of contact allergy. The importance of
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Biology of Langerhans Cells and Langerhans Cell Histiocytosis
2006Langerhans cells (LC) are epidermal dendritic cells (DC). They play an important role in the initiation of immune responses through antigen uptake, processing, and presentation to T cells. Langerhans cell histiocytosis (LCH) is a rare disease in which accumulation of cells with LC characteristics (LCH cells) occur. LCH lesions are further characterized
Robert J. Arceci, G I Bechan, R M Egeler
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The American Journal of Dermatopathology, 2006
Proliferations of Langerhans cells can be histologically divided into cytologically benign Langerhans cell proliferations, which include the clinical syndromes of Langerhans cell histiocytosis, and cytologically malignant Langerhans cell sarcoma. We report a Langerhans cell sarcoma in a 33-year-old male that arose on the posterior thigh with subsequent
John S. Metcalf+2 more
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Proliferations of Langerhans cells can be histologically divided into cytologically benign Langerhans cell proliferations, which include the clinical syndromes of Langerhans cell histiocytosis, and cytologically malignant Langerhans cell sarcoma. We report a Langerhans cell sarcoma in a 33-year-old male that arose on the posterior thigh with subsequent
John S. Metcalf+2 more
openaire +3 more sources