Results 71 to 80 of about 39,048 (228)

A conserved rule for pancreatic islet organization. [PDF]

PLoS ONE, 2014
Morphogenesis, spontaneous formation of organism structure, is essential for life. In the pancreas, endocrine α, β, and δ cells are clustered to form islets of Langerhans, the critical micro-organ for glucose homeostasis.
Danh-Tai Hoang, Hitomi Matsunari, Masaki Nagaya, Hiroshi Nagashima, J Michael Millis, Piotr Witkowski, Vipul Periwal, Manami Hara, Junghyo Jo   +8 more
doaj   +1 more source

Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. [PDF]

, 2000
Cell-cell and cell-matrix interactions play a critical role in tissue morphogenesis and in homeostasis of adult tissues. The integrin family of adhesion receptors regulates cellular interactions with the extracellular matrix, which provides three ...
Alpert, Bauer, Beattie, Beattie, Beattie, Blaschuk, Bosco, Brooks, Brooks, Calof, Cheng, Choquet, Cirulli, Cirulli, Cirulli, Clark, Clark, Dahl, DiPersio, Drake, Dudek, Ekblom, Felding-Habermann, Friedlander, George, Giancotti, Gu, Gu, Gullberg, Herrera, Herrera, Hynes, Hynes, Jaffe, Jansson, Jensen, Jones, Kantengwa, Langerhans, Langhofer, Like, Lin, Lombardi, Marchisio, Orci, Orci, Orci, Otonkoski, Otonkoski, Otonkoski, Pelletier, Pictet, Pictet, Pierschbacher, Ricordi, Rouiller, Sandler, Schwartz, Slack, Sonnenberg, Stefan, Strange, Talhouk, Teitelman, Tuch, Von Dorsche, Walker, Watt   +67 more
core   +1 more source

Pancreatic islet (of Langerhans) revisited.

Histology and histopathology, 2019
One hundred and fifty years ago, Paul Langerhans described what would come to be known as pancreatic 'islet of Langerhans'. Since then, we have accumulated knowledge about the pancreatic islet, the cells that exist there and the hormones secreted by these cells.
openaire   +3 more sources

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo [PDF]

, 2015
SCOPUS: ar.jinfo:eu-repo/semantics ...
Beyaert, Rudi, Cardozo, AK, Catrysse, Leen, Fukaya, M, Meyerovich, K, Sze, Mozes, van Loo, Geert   +6 more
core   +2 more sources

A Case of Pancreatic Neuroendocrine Tumor Growing Intraductal Extension toward the Main Pancreatic Duct Complicated by Thrombocytopenia: Diagnostic Challenges and Management Strategy

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We present a rare and diagnostically challenging case of a pancreatic neuroendocrine tumor (pNET) with intraductal growth into the main pancreatic duct (MPD), complicated by severe thrombocytopenia due to myelodysplastic syndrome. A 37‐year‐old male presented with thrombocytopenia.
Koichi Soga, Kazuma Sakakibara, Yuki Soma, Manayu Shiina, Mayumi Yamaguchi, Masaru Kuwada, Ryosaku Shirahashi, Ikuhiro Kobori, Shinichi Ban, Masaya Tamano   +9 more
wiley   +1 more source

Antidiabetic effect of honey feeding in noise induced hyperglycemic rat: involvement of oxidative stress [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s):In this study the effect of oral administration of honey on serum glucose, lipids, stress oxidative markers, and morphology of langerhans islets in noise induced hyperglycemic rats was investigated.
Saiedeh Arabmoazzen, Alireza Sarkaki, Ghasem saki, Mohammad Ali Mirshekar   +3 more
doaj  

Morphological analysis of isolated rat pancreatic islets cultured under standard culture technique and with biopolymer microstructured collagen‑containing hydrogel

Вестник трансплантологии и искусственных органов, 2017
Introduction. Extracellular matrix play an essential role in providing structural integrity and physiological support to Langerhans islets in pancreas. Imitation of the native microenvironment can be useful for viability of isolated pancreatic islets in ...
L. A. Kirsanova, N. V. Baranova, G. N. Bubentsova, V. I. Sevastianov   +3 more
doaj   +1 more source

Exercise Ameliorates Endocrine Pancreas Damage Induced by Chronic Cola Drinking in Rats [PDF]

, 2016
Purpose: This study evaluates whether the daily practice of an exercise routine might protect from endocrine pancreas damage in cola drinking rats. Methods: Forty-eight Wistar rats were randomly assigned to 4 groups depending on a) beverage consumption ...
Ambrosio, Giuseppe, Azzato, Francisco, Cao, Gabriel Fernando, Gonzalez, Julian, Milei, Jose, Muller, Maria Angelica, Otero-Losada, Matilde Estela, Ottaviano, Graciela Mabel   +7 more
core   +1 more source

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Bianca Reis Santos, Jeane Martinha dos Anjos Cordeiro, Luciano Cardoso Santos, Cleisla Souza Oliveira, Maria Clara Pascoal Santos Alvarez, Natália Panhoca Rodrigues, Jorge Lopez‐Tello, Amanda N. Sferruzzi‐Perri, Rogéria Serakides, Juneo Freitas Silva   +9 more
wiley   +1 more source

Constitutive nitric oxide synthase (cNOS) activity in Langerhans islets from streptozotocin diabetic rats

Brazilian Journal of Medical and Biological Research, 1998
Nitric oxide synthase activity was measured in Langerhans islets isolated from control and streptozotocin diabetic rats. The activity of the enzyme was linear up to 150 µg of protein from control rats and was optimal at 0.1 µM calcium, when it was ...
T.M. Fonovich de Schroeder, M.D. Carattino, M. Frontera, O.L. Catanzaro   +3 more
doaj   +1 more source