Results 181 to 190 of about 5,193 (199)

New aspects of langerin dendritic cells in patients with COPD

Airway Cell Biology and Immunopathology, 2017
Background: Alveolar antigen uptake has remained poorly investigated in human lungs and it is unclear to what extent dendritic cell (DC) subsets are altered in the alveolar parenchyma of patients with COPD. Objectives: To assess the distribution and marker profile of DCs in distal lungs of patients with COPD.
Michiko Mori, Premkumar Siddhuraj, Abraham B Roos, Martin R Stämpfli, Claes-Göran Löfdahl, Jonas S Erjefält   +5 more
openaire   +1 more source

Intestinal Regulation of C. albicans by PP Langerin+ DCs

The Journal of Immunology, 2017
Abstract As the largest mucosal compartment, the human gastrointestinal tract (GI) is highly colonized with a complex microbial ecosystem that includes fungal organisms. Although fewer in numbers and less extensively studied in the context of the intestinal mucosa, it is unclear whether commensal members such as Candida species play a ...
Magdia De Jesus, Emily Rochac-Argueta, Heather Gallagher   +2 more
openaire   +1 more source

¹⁹F NMR-Guided Design of Glycomimetic Langerin Ligands

ACS Chemical Biology, 2016
C-type lectin receptors (CLRs) play a pivotal role in pathogen defense and immune homeostasis. Langerin, a CLR predominantly expressed on Langerhans cells, represents a potential target receptor for the development of anti-infectives or immunomodulatory therapies.
Wamhoff, E., Hanske, J., Schnirch, L., Aretz, J., Grube, M., Varón Silva, D., Rademacher, C.   +6 more
openaire   +3 more sources

Langerin/CD207 positive dendritic-like cells in the haemopoietic tissues of salmonids

Fish & Shellfish Immunology, 2009
The presence of dendritic cells in fish is studied with immunohistochemistry using a commercially available antibody developed against Langerin/CD207 present in human Langerhans cells. Langerin/CD207, a protein known to be associated with the development of Birbeck granules in human and murine systems, was found to be expressed within the cytoplasm of ...
Jan, Lovy, Gayle P, Savidant, David J, Speare, Glenda M, Wright   +3 more
openaire   +2 more sources

Dectin-1 and langerin

Pilz-Beta-Glukane aktivieren die Immunantwort über verschiedene Rezeptoren, darunter C-Typ-Lektin-Rezeptoren (CLRs). Eine besondere Rolle spielt dabei Dectin-1. Frühere Studien deuteten darauf hin, dass der Dectin-1-Signalweg, der zur Interleukinproduktion führt, nur durch Hefepartikel aktiviert werden konnte, indem eine Immunsynapse gebildet wird. Die
openaire   +1 more source

Studying the relationship of annexin A2, langerin, and Birbeck granules

2018
Langerhans cells (LC) are the resident antigen presenting cells of the mucosal epithelium and play an essential role in initiating immune responses. LC are the only cells in the body to contain Birbeck granules (BG), unique cytoplasmic organelles comprised of the c-type lectin langerin.
openaire   +1 more source

Depletion of langerin+ cells enhances cutaneous wound healing

Immunology, 2020
Aarthi Rajesh, Lyn M Wise, Merilyn Hibma   +2 more
exaly  

Langerin

2008
openaire   +1 more source

C-type lectin Langerin is a β-glucan receptor on human Langerhans cells that recognizes opportunistic and pathogenic fungi

Molecular Immunology, 2010
Marein A W P De Jong, Maureen E Taylor, Teun Boekhout   +2 more
exaly  

Langerin

2011
openaire   +1 more source