Results 101 to 110 of about 195,033 (294)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Did Dog Domestication Contribute to Language Evolution? [PDF]
Benítez-Burraco A, Pörtl D, Jung C.
europepmc +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Legal Languages – A Diachronic Perspective
The aim of the article is to discuss the legal language transformations from a diachronic perspective taking into account the following factors: (i) spatial and temporal, (ii) linguistic norm changes, (iii) political, (iv) social (customs), and (v ...
Matulewska Aleksandra
doaj +1 more source
Learning the protein language: Evolution, structure, and function. [PDF]
Bepler T, Berger B.
europepmc +1 more source
Learning Bias, Cultural Evolution of Language, and the Biological Evolution of the Language Faculty [PDF]
The biases of individual language learners act to determine the learnability and cultural stability of languages: learners come to the language learning task with biases which make certain linguistic systems easier to acquire than others. These biases are repeatedly applied during the process of language transmission, and consequently should effect the
openaire +2 more sources
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Major Transitions in Language Evolution
: Language is the most important evolutionary invention of the last few million years. How human language evolved from animal communication is a challenging question for evolutionary biology.
Martin A. Nowak, Joshua B. Plotkin
doaj +1 more source
Emerging Grounded Shared Vocabularies Between Human and Machine, Inspired by Human Language Evolution. [PDF]
Kouwenhoven T +3 more
europepmc +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source

