Results 101 to 110 of about 149,518 (260)
Language evolution: examining the link between cross-modality and aggression through the lens of disorders. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2021 Benítez-Burraco A, Progovac L.
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Sobre una concepción inadecuada de la doble articulación [PDF]
Sintagma, 2010 Although double articulation is considered to be one of the core features of human language, not much attention has been paid to it in the field of language origins and evolution.
Víctor M. Longa, Juan J. López Rivera
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Disentangling Pantomime From Early Sign in a New Sign Language: Window Into Language Evolution Research. [PDF]
Front Psychol, 2021 Mineiro A +4 more
europepmc +1 more source
Language Evolution, Metasyntactically
Electron. Commun. Eur. Assoc. Softw. Sci. Technol., 2012 Vadim Zaytsev. Language Evolution, Metasyntactically. To appear in The Pre-proceedings of the First International Workshop on Bidirectional Transformation (BX 2012), March 2012.
openaire +5 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Human language evolution: a view from theoretical linguistics on how syntax and the lexicon first came into being. [PDF]
Primates, 2022 Fujita H, Fujita K.
europepmc +1 more source
2008 15th Working Conference on Reverse Engineering, 2008 By abstraction and factoring out domain specific knowledge, model driven engineering addresses the problem of increasing software complexity. Both models and meta models are generally subject to evolution, yet evolution of a meta model can cause conforming models to no longer conform and thereby no longer be usable.
openaire +3 more sources
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source