Results 111 to 120 of about 195,033 (294)

Symbol Emergence as an Interpersonal Multimodal Categorization

open access: yesFrontiers in Robotics and AI, 2019
This study focuses on category formation for individual agents and the dynamics of symbol emergence in a multi-agent system through semiotic communication.
Yoshinobu Hagiwara   +3 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Beyond bigrams: call sequencing in the common marmoset (Callithrix jacchus) vocal system

open access: yesRoyal Society Open Science
Over the last two decades, an emerging body of research has demonstrated that non-human animals exhibit the ability to combine context-specific calls into larger sequences.
Alexandra B. Bosshard   +5 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Experiments in Cultural Language Evolution

open access: yes
Human natural languages use quantifiers as ways to designate the number of objects of a set. They include numerals, such as ``three'', or circumscriptions, such as ``a few''. The latter are not only underdetermined but also context dependent.
Steels, Luc.
core  

From holism to compositionality: memes and the evolution of segmentation, syntax, and signification in music and language

open access: yes, 2015
Steven Mithen argues that language evolved from an antecedent he terms “Hmmmmm, [meaning it was] Holistic, manipulative, multi-modal, musical and mimetic”.
Jan, Steven
core   +1 more source

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