Results 51 to 60 of about 1,941,607 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

De la conception utilitaire de la langue en traduction [PDF]

open access: yesÇédille: Revista de Estudios Franceses, 2012
From translation theorists general point of view, translator and interpreter are bilingual and translate towards their mother tongue. This vision involves taking for granted the mastery of foreign language and culture.
Daniela Ventura
doaj  

La tâche pédagogique au service du développement des savoir-faire langagiers et professionnels. Exemple de français des affaires

open access: yesGlottodidactica, 2020
Task Based Learning / Teaching focuses on the action dimension of language use, i.e., various tasks performed every day that require cooperation with others and the mobilization of language. Language proves to be the most important instrument of action,
Magdalena Sowa
doaj   +1 more source

Esp for Efl: Roles and Methodology in Elt Class [PDF]

open access: yes, 2015
Foreign Language Teachers for Specific Purposes have a lot in common with teachers of general foreign language. For both it is necessary to consider linguistic development and teaching theories, to have insights in contemporary ideas regarding their own ...
Lestari, R. C. (Rahmi)
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A UML/OCL framework for the analysis of fraph transformation rules [PDF]

open access: yes, 2009
In this paper we present an approach for the analysis of graph transformation rules based on an intermediate OCL representation. We translate different rule semantics into OCL, together with the properties of interest (like rule applicability, conflicts ...
Cabot Sagrera, Jordi   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Academic literacies approaches for facilitating language for specific purposes [PDF]

open access: yesIbérica, 2011
This paper offers a possible framework for working with language for specific purposes (LSP) in an integrated fashion, i.e. with disciplinary learning as the main lever to promote academic literacy.
Magnus Gustafsson
doaj   +2 more sources

Профессиональная направленность при обучении английскому языку студентов неязыковых специальностей [PDF]

open access: yes, 2004
Предметом статьи является эффективность использования новой технологии при обучении и изучении английского языка с профессиональной направленностью.Предметом статті є ефективність використання нової технології під час навчання та вивчення англійської ...
Hamers, Timo   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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