Results 71 to 80 of about 198,713 (266)
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Voice Onset Time (VOT) in L1 Slovenian Voiceless Stops and Its Transfer to L2 English
Slavia MeridionalisThe study investigates the Voice Onset Time (VOT) characteristics of Slovenian native speakers producing voiceless plosives in Slovenian and English. Building on foundational research by Lisker and Abramson (1964), the analysis aims to fill a gap in VOT
Andrej Stopar
doaj +1 more source
Cross-linguistic Influence in Third Language Acquisition: Factors Influencing Interlanguage Transfer
Working Papers in Applied Linguistics and TESOL, 2015 In the field of Second Language Acquisition (SLA), the role of transfer has been theorized and studied to account for the influence of the native language on an interlanguage.
Tammy Wang
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
LanguagesThis study investigates how Chinese learners of English express manners of motion, examining systematic features, cognitive motivations, and compensatory strategies.
Haiyan Zhu
doaj +1 more source
PRAGMATIC TRANSFER OF ALGERIAN LEARNERS IN LEARNING ENGLISH AS A THIRD LANGUAGE
Indonesian Journal of Learning and Instruction, 2019 The recent developments in cognitive linguistics turn EFL research interest to investigate the role of pragmatic aspects in the learn ability of English instead of grammar-governed learning.
Belfarhi Allia Khadija
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FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Glottodidactica, 2015 Interlingual transfer is a well known phenomenon. Thanks to many psycholinguistic studies it is now known which factors can induce or hinder this kind of transfer.
Zofia Chłopek
doaj +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source