Results 181 to 190 of about 17,586 (206)

Post-lanosterol biosynthesis of cholesterol and cancer

Current Opinion in Pharmacology, 2012
Mammalian cells require cholesterol for proliferation. Cholesterol contributes not only to the physicochemical properties of membranes but also to the organization of lipid rafts involved in signal transduction. Inhibition of cholesterol biosynthesis from lanosterol results in the inhibition of cell cycle progression and, in certain cell types, also in
Miguel A, Lasunción, Covadonga, Martín-Sánchez, Alberto, Canfrán-Duque, Rebeca, Busto   +3 more
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New Aspects on Lanosterol 14α-Demethylase and Cytochrome P450 Evolution: Lanosterol/Cycloartenol Diversification and Lateral Transfer

Journal of Molecular Evolution, 2004
Sterol 14alpha-demethylase (CYP51) is a member of the cytochrome P450 superfamily, widely found in animals, fungi, and plants but present in few prokaryotic groups. CYP51 is currently believed to be the ancestral cytochrome P450 that has been transferred from prokaryotes to eukaryotic kingdoms.
Tadeja, Rezen, Natasa, Debeljak, Dusan, Kordis, Damjana, Rozman   +3 more
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Cholesterol Biosynthesis: Lanosterol to Cholesterol

Journal of Chemical Education, 2002
Cholesterol is an important biochemical, medical, and commercial molecule. In the pathway for cholesterol biosynthesis, biochemistry textbooks discuss the synthesis of lanosterol from acetate in detail. However, the conversion of lanosterol to cholesterol is most often simply indicated as a multistep process, without elaboration.
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Lanosterol 14α-Demethylase (Cytochrome P45014DM)

1993
Lanosterol 14α-demethylase (cytochrome P45014DM) is a housekeeping enzyme occurring widely in eukaryotes. It is a cytochrome P450 mono-oxygenase catalyzing the conversion of lanosterol or 24,25-dihydrolanosterol (DHL) to the 14-demethylated and 14,15-desaturated derivatives by removing the 14α-methyl group (C32) as formic acid (Fig.
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Lanosterol

Nature, 1944
C. DORÉE, J. F. MCGHIE
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lanosterol, n.

2023
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37. Lanosterol. Part II. The oxidation of lanosterol with chromic acid

J. Chem. Soc., 1941
Lionel J. Bellamy, Charles Dorée
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181. Lanosterol. Part XI. Reduction of ketones in the lanosterol series

Journal of the Chemical Society (Resumed), 1951
J. F. Cavalla, J. F. McGhie
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345. Lanosterol. Part I

J. Chem. Soc., 1936
Charles Dorée, Vladimir A. Petrow
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Lanosterol

2007
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