Results 1 to 10 of about 42,267 (230)
Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes. [PDF]
PLoS ONE, 2015 Several microalgae accumulate high levels of squalene, and as such provide a potentially valuable source of this useful compound. However, the molecular mechanism of squalene biosynthesis in microalgae is still largely unknown.
Masataka Kajikawa +5 more
doaj +4 more sources
Squalene Emulsions for Parenteral Vaccine and Drug Delivery
Molecules, 2009 Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented.
Christopher B Fox
exaly +3 more sources
Production of squalene by squalene synthases and their truncated mutants in Escherichia coli [PDF]
Journal of Bioscience and Bioengineering, 2015 Squalene is a precursor of thousands of bioactive triterpenoids and also has industrial value as a lubricant, health-promoting agent, and/or drop-in biofuel. To establish an efficient Escherichia coli-based system for squalene production, we tested two different squalene synthases and their mutants in combination with precursor pathways.
Ling Li +2 more
exaly +3 more sources
Frontiers in Nutrition, 2022 Squalene is a precursor of steroids with diverse bioactivities. Tea was previously found to contain squalene, but its variation between tea cultivars remains unknown.
Yue Yue Sheng +8 more
doaj +1 more source
Squalene Supplementation as a Novel to Increase PUFA Content in Fish Tissues
Animals, 2023 Squalene is an antioxidant that plays an essential role in fat metabolism. The study aimed to assess the effect of squalene supplied in feed on the growth performance, health status, and fatty acid profiles of muscle and liver of Siberian sturgeon ...
Piotr Niewiadomski +9 more
doaj +1 more source
Metadata analysis of the squalene epoxidase gene in dermatophytes.
International Journal of Endorsing Health Science Research, 2021 Background:Squalene epoxidase gene is an azole antifungal target enzyme in the ergosterol biosynthesis pathway in fungi—the inhibition of enzyme aggregate squalene, a type of ergosterol derivative depletion that leads to fungal growth inhibition.
Fatima Ismail, Iqra Ahmad, Eqaza Javed
doaj +1 more source
Analysis of Antidiabetic Activity of Squalene via In Silico and In Vivo Assay
Molecules, 2023 Squalene has been tested widely in pharmacological activity including anticancer, antiinflammatory, antioxidant, and antidiabetic properties. This study aims to examine antidiabetic activity of squalene in silico and in vivo models.
Tri Widyawati +3 more
doaj +1 more source
BIO Web of Conferences, 2021 Squalene is a naturally-occurring dihydro-triterpene hydrocarbon (C30H50) with six double bonds, which is an intermediate in the biosynthesis of phytosterol or cholesterol in plants or animals.
Dubrovskaya Irina +3 more
doaj +1 more source
Metabolic Engineering Communications, 2020 Squalene is a triterpene which is produced as a precursor for a wide range of terpenoid compounds in many organisms. It has commercial use in food and cosmetics but could also be used as a feedstock for production of chemicals and fuels, if generated ...
Bagmi Pattanaik +3 more
doaj +1 more source
Squalene synthase inhibitors [PDF]
British Journal of Pharmacology, 2003 British Journal of Pharmacology (2003) 139, 881–882.
V C, Menys, P N, Durrington
openaire +2 more sources