Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica [PDF]
Synthetic and Systems BiotechnologySqualene, a multifunctional natural compound with diverse bioactivities, has significant potential in the nutraceutical and health industries. Microbial synthesis using engineered cell factories represents a sustainable alternative to conventional ...
Qiao-Qin Zhao +10 more
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Production of squalene and fatty acids by Thraustochytrium sp. RT2316-16: effects of dissolved oxygen and the medium composition [PDF]
Bioresources and BioprocessingThraustochytrium sp. RT2316-16 is a versatile marine microbe that produces useful compounds including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), carotenoids and coenzyme Q10.
Paris Paredes +5 more
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Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review [PDF]
, 2020 Polymyalgia rheumatica (PMR) is the most common inflammatory rheumatological condition affecting individuals aged >50 years. There have been rare reports of PMR and other vasculitides developing within 3 months of influenza vaccination.
Bassendine, Margaret F., Bridge, Simon
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Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors. [PDF]
, 2020 Marine sponge holobionts, defined as filter-feeding sponge hosts together with their associated microbiomes, are prolific sources of natural products. The inventory of natural products that have been isolated from marine sponges is extensive. Here, using
Agarwal, Vinayak +5 more
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Plasma squalene: lipoprotein distribution and kinetic analysis.
Journal of Lipid Research, 1978 Plasma squalene concentration is increased in hypertriglyceridemia. In 24 normotriglyceridemic and 12 hypertriglyceridemic subjects, whole plasma squalene correlated strongly with plasma triglyceride (r = 0.973, P < 0.001) in the latter.
C D Saudek, B M Frier, G C Liu
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Frontiers in Microbiology, 2022 Squalene, a natural lipid of the terpenoid family, is well-recognized for its roles in regulating cholesterol metabolism, preventing tumor development, and improving immunity.
Aiqing Zhang +7 more
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Biotechnology for Biofuels, 2019 Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial fermentation processes for squalene production have been emerging over recent years.
Wen Xu +6 more
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Production of squalene in Synechocystis sp. PCC 6803. [PDF]
PLoS ONE, 2014 In recent years, there has been an increased interest in the research and development of sustainable alternatives to fossil fuels. Using photosynthetic microorganisms to produce such alternatives is advantageous, since they can achieve direct conversion ...
Elias Englund +5 more
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Squalene Biosynthesis in Engineered Escherichia Coli
Pharmaceutical Fronts, 2023 Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang +3 more
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Molecular Identification of Native Strain of Thraustochytrium 71-1 and Qualitative and Quantitative Determination of Produced Total Oil and its Squalene [PDF]
Biological Journal of Microorganism, 2019 Introduction:Squalene is a polyunsaturated hydrocarbon with six double bonds. Squalene has many applications in biofuel, cosmetic, medical and pharmaceutical industries.
farshad khoshbasirat +2 more
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