Results 11 to 20 of about 26,244 (230)

Introduction of a green algal squalene synthase enhances squalene accumulation in a strain of Synechocystis sp. PCC 6803 [PDF]

open access: yesMetabolic Engineering Communications, 2020
Squalene is a triterpene which is produced as a precursor for a wide range of terpenoid compounds in many organisms. It has commercial use in food and cosmetics but could also be used as a feedstock for production of chemicals and fuels, if generated ...
Bagmi Pattanaik   +3 more
doaj   +2 more sources

Production of squalene in Synechocystis sp. PCC 6803. [PDF]

open access: yesPLoS ONE, 2014
In recent years, there has been an increased interest in the research and development of sustainable alternatives to fossil fuels. Using photosynthetic microorganisms to produce such alternatives is advantageous, since they can achieve direct conversion ...
Elias Englund   +5 more
doaj   +3 more sources

Squalene through its post-squalene metabolites is a modulator of hepatic transcriptome in rabbits [PDF]

open access: yes, 2022
Squalene is a natural bioactive triterpene and an important intermediate in the biosynthesis of sterols. To assess the effect of this compound on the hepatic transcriptome, RNA-sequencing was carried out in two groups of male New Zealand rabbits fed ...
Lasunción, M. A.   +10 more
core   +3 more sources

Study of the Effect of Squalene Epoxidase Activity on Squalene Biosynthesis by Yeast Saccharomyces Cerevisiae VGSh-2 [PDF]

open access: yes, 2022
The researchers of this study investigated the biosynthesis of squalene by the yeast S. cerevisiae VGSH-2 through the activity of squalene epoxidase, which is a key enzyme in the conversion of squalene to ergosterol.
Shuvaeva, Galina P.   +9 more
core   +2 more sources

Plasma squalene: lipoprotein distribution and kinetic analysis.

open access: yesJournal of Lipid Research, 1978
Plasma squalene concentration is increased in hypertriglyceridemia. In 24 normotriglyceridemic and 12 hypertriglyceridemic subjects, whole plasma squalene correlated strongly with plasma triglyceride (r = 0.973, P < 0.001) in the latter.
C D Saudek, B M Frier, G C Liu
doaj   +1 more source

Squalene synthase inhibitors [PDF]

open access: yesBritish Journal of Pharmacology, 2003
British Journal of Pharmacology (2003) 139, 881–882.
V C, Menys, P N, Durrington
openaire   +2 more sources

Analysis of squalene accumulation. [PDF]

open access: yes, 2014
Squalene was extracted from wild type and Δshc cultures and the extracts analyzed by HPLC using a squalene standard for identification and quantification of the squalene peak. The identity of the squalene peak was confirmed using GC-MS.
Sarojini Jayantha K. Ubhayasekera (535347)   +5 more
core   +1 more source

Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying the isoprenoid-feeding module and blocking the menaquinone pathway in Escherichia coli

open access: yesBiotechnology for Biofuels, 2019
Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial fermentation processes for squalene production have been emerging over recent years.
Wen Xu   +6 more
doaj   +1 more source

Optimal NaCl Medium Enhances Squalene Accumulation in Thraustochytrium sp. ATCC 26185 and Influences the Expression Levels of Key Metabolic Genes

open access: yesFrontiers in Microbiology, 2022
Squalene, a natural lipid of the terpenoid family, is well-recognized for its roles in regulating cholesterol metabolism, preventing tumor development, and improving immunity.
Aiqing Zhang   +7 more
doaj   +1 more source

Overexpression of the Arabidopsis thaliana squalene synthase gene in Withania coagulans hairy root cultures [PDF]

open access: yes, 2011
Squalene synthase (SS) dimerizes two molecules of farnesyl diphosphate to synthesize squalene, a shared precursor in steroid and triterpenoid biosynthesis in plants.
M. H. Mirjalili   +4 more
core   +1 more source

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