Results 21 to 30 of about 29,092 (237)
Molecular Identification of Native Strain of Thraustochytrium 71-1 and Qualitative and Quantitative Determination of Produced Total Oil and its Squalene [PDF]
Biological Journal of Microorganism, 2019 Introduction:Squalene is a polyunsaturated hydrocarbon with six double bonds. Squalene has many applications in biofuel, cosmetic, medical and pharmaceutical industries.
farshad khoshbasirat +2 more
doaj +1 more source
Squalene Biosynthesis in Engineered Escherichia Coli
Pharmaceutical Fronts, 2023 Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang +3 more
doaj +1 more source
Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase. [PDF]
PLoS ONE, 2016 Ataxia telangiectasia mutated (ATM) kinase plays a crucial role as a master controller in the cellular DNA damage response. Inhibition of ATM leads to inhibition of the checkpoint signaling pathway.
Naoto Tatewaki +8 more
doaj +1 more source
Integrated Experimental, Chemometric, and In Silico Analyses of Larvicidal Supercritical Extracts From Myrtaceae Species Against Aedes aegypti. [PDF]
Chem BiodiversThe cross‐validated regression tree showed modest predictive performance. Mortality was not significantly associated with the first two PCA axes. Molecular modeling generated testable ligand–target hypotheses. Psidium cattleianum had lower LD50. The larvicidal activity of the crude extracts could not be attributed to individual constituents.
Bones UA +8 more
europepmc +2 more sources
Squalene-Hopene Cyclases [PDF]
Applied and Environmental Microbiology, 2011 ABSTRACTHopanoids and sterols are members of a large group of cyclic triterpenoic compounds that have important functions in many prokaryotic and eukaryotic organisms. They are biochemically synthesized from linear precursors (squalene, 2,3-oxidosqualene) in only one enzymatic step that is catalyzed by squalene-hopene cyclase (SHC) or oxidosqualene ...
Gabriele, Siedenburg, Dieter, Jendrossek
openaire +2 more sources
Journal of Lipid Research, 1980 When rat liver cytosol, possessing sterol carrier protein (SCP) activity was incubated with [3H]-squalene-phospholipid liposomes, cofactors, and rat liver microsomes, squalene from the liposomes was converted into sterols.
R J Morin, M V Srikantaiah
doaj +1 more source
Poultry Science, 2020 This study was conducted to evaluate the effects of dietary squalene supplementation on the growth performance, plasma biochemical indices, antioxidant status, and meat quality in broilers.
Yueping Chen +4 more
doaj +1 more source
Frontiers in Chemical Engineering, 2022 Squalene is an important polyunsaturated triterpene with wide applications in the food, cosmetics, and pharmaceutical industries. Currently, the main method for squalene production is extraction from oil-producing plants, but the scale is limited.
Lu Xia +13 more
doaj +1 more source
Genome-Wide Identification and Structural Characterization of Secondary Metabolite Biosynthetic Gene Clusters in African Baobab (Adansonia digitata). [PDF]
Chem BiodiversGenome‐wide computational analysis of the African baobab (Adansonia digitata) identifies 50 candidate biosynthetic gene clusters spanning terpene, polyketide, cyclopeptide, and lignan pathways, including nine BURP‐domain clusters linked to putative chemical defense.
Elshikh AA, Kabbashi AS, Musa IM.
europepmc +2 more sources
Production of squalene by squalene synthases and their truncated mutants in Escherichia coli [PDF]
Journal of Bioscience and Bioengineering, 2015 Squalene is a precursor of thousands of bioactive triterpenoids and also has industrial value as a lubricant, health-promoting agent, and/or drop-in biofuel. To establish an efficient Escherichia coli-based system for squalene production, we tested two different squalene synthases and their mutants in combination with precursor pathways.
Katabami, Akinori +5 more
openaire +2 more sources