Optimisation of squalene recovery from palm oil by-product using integrated sc-CO2-pressure swing [PDF]
, 2018 Squalene is used as an ingredient in functional foods, pharmaceuticals, and cosmetics. Due to the limitation of squalene availability from predominant source which is shark liver oil and to sustain the environment by fully utilising the by-product of ...
Baharin, Badlishah Sham +5 more
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Fate of intravenously administered squalene and plant sterols in human subjects
Journal of Lipid Research, 2001 We have studied metabolism of plant sterols and squalene administered intravenously in the form of lipid emulsion mimicking chylomicrons (CM). The CM-like lipid emulsion was prepared by dissolving squalene in commercially available Intralipid®.
Heikki Relas +2 more
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Molecular Identification of Native Strain of Thraustochytrium 71-1 and Qualitative and Quantitative Determination of Produced Total Oil and its Squalene [PDF]
Biological Journal of Microorganism, 2019 Introduction:Squalene is a polyunsaturated hydrocarbon with six double bonds. Squalene has many applications in biofuel, cosmetic, medical and pharmaceutical industries.
farshad khoshbasirat +2 more
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Squalene Biosynthesis in Engineered Escherichia Coli
Pharmaceutical Fronts, 2023 Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang +3 more
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Squalene-PEG-Exendin as High-Affinity Constructs for Pancreatic Beta-Cells [PDF]
, 2018 Novel drug delivery systems targeting native, transplanted, or cancerous beta-cells are of utmost importance. Herein, we present new exendin-4 derivatives with modified unnatural amino acids at strategic positions within the polypeptide sequence.
Andrej Babič (5548550) +5 more
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Functional Characterization of Four Olive Squalene Synthases with Respect to the Squalene Content of the Virgin Olive Oil [PDF]
, 2023 The release of new olive cultivars with an increased squalene content in their virgin olive oil is considered an important target in olive breeding programs. In this work, the variability of the squalene content in a core collection of 36 olive cultivars
Raquel B. Gómez-Coca (17125224) +8 more
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Squalene uptake in cultured cells. [PDF]
, 2016 Squalene uptake by A549 adenocarcinoma cells. The cells were incubated with various concentrations of squalene (0–300 μM) for 3 h, washed in PBS, and harvested.
Miyako Nishida (2177782) +8 more
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Squalene-Hopene Cyclases [PDF]
Applied and Environmental Microbiology, 2011 ABSTRACTHopanoids and sterols are members of a large group of cyclic triterpenoic compounds that have important functions in many prokaryotic and eukaryotic organisms. They are biochemically synthesized from linear precursors (squalene, 2,3-oxidosqualene) in only one enzymatic step that is catalyzed by squalene-hopene cyclase (SHC) or oxidosqualene ...
Gabriele, Siedenburg, Dieter, Jendrossek
openaire +2 more sources
Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase. [PDF]
PLoS ONE, 2016 Ataxia telangiectasia mutated (ATM) kinase plays a crucial role as a master controller in the cellular DNA damage response. Inhibition of ATM leads to inhibition of the checkpoint signaling pathway.
Naoto Tatewaki +8 more
doaj +1 more source
Journal of Lipid Research, 1980 When rat liver cytosol, possessing sterol carrier protein (SCP) activity was incubated with [3H]-squalene-phospholipid liposomes, cofactors, and rat liver microsomes, squalene from the liposomes was converted into sterols.
R J Morin, M V Srikantaiah
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