Results 31 to 40 of about 26,244 (230)

Effects of graded levels of dietary squalene supplementation on the growth performance, plasma biochemical parameters, antioxidant capacity, and meat quality in broiler chickens

open access: yesPoultry Science, 2020
This study was conducted to evaluate the effects of dietary squalene supplementation on the growth performance, plasma biochemical indices, antioxidant status, and meat quality in broilers.
Yueping Chen   +4 more
doaj   +1 more source

The Promiscuity of Squalene Synthase-Like Enzyme: Dehydrosqualene Synthase, a Natural Squalene Hyperproducer? [PDF]

open access: yes
Dehydrosqualene synthase (CrtM), as a squalene synthase-like enzyme from Staphylococcus aureus, can naturally utilize farnesyl diphosphate to produce dehydrosqualene (C30H48).
Marcel de Vries (354275)   +7 more
core   +4 more sources

Enhancing Squalene Production in Saccharomyces cerevisiae by Metabolic Engineering and Random Mutagenesis

open access: yesFrontiers in Chemical Engineering, 2022
Squalene is an important polyunsaturated triterpene with wide applications in the food, cosmetics, and pharmaceutical industries. Currently, the main method for squalene production is extraction from oil-producing plants, but the scale is limited.
Lu Xia   +13 more
doaj   +1 more source

Unveiling an unexpected superoxide-mediated photooxidation mechanism of squalene monohydroperoxides to squalene hydroperoxy cyclic peroxides through ESR and LC-MS/MS analyses [PDF]

open access: yes, 2023
Lipid cyclic peroxides are a rarely reported and documented class of compounds in the human organism. Recently, we reported the formation of squalene (SQ) hydroperoxy cyclic peroxides derived from SQ monohydroperoxide isomers (SQ-OOHs) for the first time.
Kiyotaka , Nakagawa   +2 more
core   +1 more source

Metabolic variables of cholesterol during squalene feeding in humans: comparison with cholestyramine treatment

open access: yesJournal of Lipid Research, 1990
Squalene, a key intermediate of cholesterol synthesis, is present especially in olive oil. Regulation of cholesterol metabolism by dietary squalene in man is unknown, even though olive oil users in Mediterranean areas have low serum cholesterol levels ...
TE Strandberg, RS Tilvis, TA Miettinen
doaj   +1 more source

Functional characterization of squalene synthase and squalene epoxidase in Taraxacum koksaghyz [PDF]

open access: yesPlant Direct, 2018
AbstractThe Russian dandelion Taraxacum koksaghyz produces high‐value isoprenoids such as pentacyclic triterpenes and natural rubber in the latex of specialized cells known as laticifers. Squalene synthase (SQS) and squalene epoxidase (SQE) catalyze key steps in the biosynthesis of cyclic terpenoids, but neither enzyme has yet been characterized in T ...
Unland, Kristina   +6 more
openaire   +2 more sources

Squalene Selectively Protects Mouse Bone Marrow Progenitors Against Cisplatin and Carboplatin-Induced Cytotoxicity In Vivo Without Protecting Tumor Growth

open access: yesNeoplasia: An International Journal for Oncology Research, 2008
Squalene, an isoprenoid antioxidant is a potential cytoprotective agent against chemotherapy-induced toxicity. We have previously published that squalene protects light-density bone marrow cells against cis-diamminedichloroplatinum( II) (cisplatin ...
Bikul Das   +9 more
doaj   +1 more source

Determination of squalene in edible oils by transmethylation and GC analysis

open access: yesMethodsX, 2019
Squalene is a triterpenoid with medicinal, therapeutic and cosmetic applications. There is interest in identifying novel sources of squalene, creating a need for a rapid and accurate method of squalene determination.
Suzanne M. Budge, Christopher Barry
doaj   +1 more source

Squalene enhances γIR toxicity. [PDF]

open access: yes, 2016
Relative cell viability was measured by a clonogenic assay. (A) Cytotoxicity of squalene (0, 1, 3, 10, 30, and 100 μM) was measured after 14 days of incubation. (B) and (C) Impact of squalene on radiation toxicity.
Miyako Nishida (2177782)   +8 more
core   +1 more source

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