Autonomous AI‐Driven Design for Skin Product Formulations
Advanced Intelligent Discovery, EarlyView.This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Squalene monooxygenase – a target for hypercholesterolemic therapy [PDF]
, 2011 Squalene monooxygenase catalyzes the epoxidation of C-C double bond of squalene to yield 2,3-oxidosqualene, the key step of sterol biosynthesis pathways in eukaryotes.
Jan Barciszewski +5 more
core +1 more source
Sustainable biosynthesis of squalene from waste cooking oil by the yeast Yarrowia lipolytica
Metabolic Engineering CommunicationsSqualene is a highly sought-after triterpene compound in growing demand, and its production offers a promising avenue for circular economy practices.
Shuhui Wang +8 more
doaj +1 more source
Molecules, 2022 UV-induced oligomerisation of squalene was undertaken to indicate the potential for squalene-containing biological systems to exhibit rheology changes.
Matteo Zecchini +5 more
doaj +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
BMEMat, EarlyView.Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Genotoxicity assessment of vaccine adjuvant squalene [PDF]
, 2013 The genotoxic potential of the vaccine adjuvant Squalene was assessed by the chromosomal aberrations (CAs), sister chromatid exchanges (SCEs) and micronucleus (MNs) tests in human lymphocytes and comet assay in both human and rat lymphocytes.
Aksoy, Hüseyin
core +1 more source
Recent advances in the microbial production of squalene. [PDF]
, 2022 Squalene is a triterpene hydrocarbon, a biochemical precursor for all steroids in plants and animals. It is a principal com ponent of human surface lipids, in particular of sebum.
Kalaivani, Paramasivan, Sarma, Mutturi
core +1 more source
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ChemFoodChem, EarlyView.ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Extraction and enrichment of minor lipid components of palm fatty acid distillate using supercritical carbon dioxide [PDF]
, 2012 Currently the extraction of valuable components from oils is of growing interest. Palm fatty acid distillate is a by-product from palm oil refining process which contains valuable minor components.
Al-Darmaki, Naeema Ibrahim Karam
core
Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock [PDF]
, 2014 Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine ...
Diane E Kelly +16 more
core +1 more source