Results 41 to 50 of about 29,092 (237)

Green Microalgae Strain Improvement for the Production of Sterols and Squalene

Plants, 2021
Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun, Suparat Jaingam, Nuttha Sanevas, Srunya Vajrodaya, Anchalee Sirikhachornkit   +4 more
doaj   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source

Squalene Loaded Nanoparticles Effectively Protect Hepatic AML12 Cell Lines against Oxidative and Endoplasmic Reticulum Stress in a TXNDC5-Dependent Way

Antioxidants, 2022
Virgin olive oil, the main source of fat in the Mediterranean diet, contains a substantial amount of squalene which possesses natural antioxidant properties. Due to its highly hydrophobic nature, its bioavailability is reduced.
Seyed Hesamoddin Bidooki, Teresa Alejo, Javier Sánchez-Marco, Roberto Martínez-Beamonte, Roubi Abuobeid, Juan Carlos Burillo, Roberto Lasheras, Victor Sebastian, María J. Rodríguez-Yoldi, Manuel Arruebo, Jesús Osada   +10 more
doaj   +1 more source

Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock [PDF]

, 2014
Squalene is a polyunsaturated triterpenic hydrocarbon with nutritional, cosmetic, pharmaceutical and medical applications. given the increasing commercial demand for squalene alongside growing international concern for the fate of food crops and marine ...
Diane E Kelly, E Loveridge, Joel Loveridge, Claire Hull, E Joel Loveridge, Donnison, Iain S, Rolley, Nicola J, Kelly, Diane E, Steven Kelly, Loveridge, Edric Joel, Steven L Kelly, Nicola J Rolley, Claire M Hull, Kelly, Steven L, Diane Kelly, Iain S Donnison, Hull, Claire M   +16 more
core   +2 more sources

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Squalene — a natural biologically active component of nutrition of the 21st century

Пищевые системы
Squalene is a carbon-containing organic compound of the triterpene series. It is a precursor of many vitamins, hormones and sterols in a body of mammals, plants, fungi and bacteria. The purpose of this scientific literature review was to systematize data
E. V. Ulrikh, S. A. Sukhikh, I. G. Samusev, O. O. Babich   +3 more
doaj   +1 more source

Dietary squalene supplementation alleviates diquat-induced oxidative stress and liver damage of broiler chickens

Poultry Science, 2021
The aim of this study was to explore the protective effects of squalene supplementation on growth performance, oxidative status, and liver function of diquat-challenged broilers.
Y.P. Chen, Y.F. Gu, H.R. Zhao, Y.M. Zhou
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Sustainable biosynthesis of squalene from waste cooking oil by the yeast Yarrowia lipolytica

Metabolic Engineering Communications
Squalene is a highly sought-after triterpene compound in growing demand, and its production offers a promising avenue for circular economy practices.
Shuhui Wang, Xu Sun, Yuqing Han, Zhuo Li, Xiaocong Lu, Hongrui Shi, Cui-ying Zhang, Adison Wong, Aiqun Yu   +8 more
doaj   +1 more source

Investigation of the Formation of Squalene Oligomers Exposed to Ultraviolet Light and Changes in the Exposed Squalene as a Potential Skin Model

Molecules, 2022
UV-induced oligomerisation of squalene was undertaken to indicate the potential for squalene-containing biological systems to exhibit rheology changes.
Matteo Zecchini, Robert A. Lucas, Cameron Robertson, Tomris Coban, Ravtej Thatti, Adam Le Gresley   +5 more
doaj   +1 more source