Results 11 to 20 of about 10,268 (212)

Safety of Proton Pump Inhibitor in Paediatrics: A Study Based on EudraVigilance Data [PDF]

Fundamental &Clinical Pharmacology, Volume 39, Issue 4, August 2025.
ABSTRACT Background and Objectives Despite limited paediatric approvals, the use of proton pump inhibitors (PPIs) among children has increased in recent years, and concerns have arisen about their safety, including the risk of allergies. To provide additional evidence on the paediatric safety of PPIs, we performed a study on suspected adverse drug ...
Greta Santi Laurini, Victoria Nikitina, Nicola Montanaro, Domenico Motola   +3 more
wiley   +2 more sources

A case of late‐onset psychosis secondary to traumatic brain injury difficult to differentiate from delirium [PDF]

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.
Traumatic brain injury (TBI) causes psychotic disorders to occur in a delayed‐onset form in certain cases. In this report, we present a case of psychotic disorders due to TBI with a sudden delirium‐like onset nearly 20 years after the traumatic injury, posing significant challenges for differential diagnosis. Abstract Background Traumatic brain injury (
Tomonobu Kato, Takashi Tsujii, Hisashi Kida, Daiki Mochizuki, Shigeru Nikkuni, Kei Sakuma   +5 more
wiley   +2 more sources

Trends in Proton‐Pump Inhibitor Use Among Danish Adults: A Nationwide Drug Utilization Study 2015–2023 [PDF]

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.
ABSTRACT The global increase in proton‐pump inhibitor (PPI) use has raised concerns about their appropriate use, particularly due to potential overprescription and associated adverse effects. This study examines PPI utilization patterns among Danish adults from 2015 to 2023 using the Danish nationwide health registries.
Karoline M. Lundgaard, Morten Ø. Christiansen, Heidi Sonne, Katrine Mose, Nikolaj Nyland, Maja J. L. Andersen, Anton Pottegård   +6 more
wiley   +2 more sources

Efficacy and safety of vonoprazan versus proton pump inhibitors in the treatment of peptic ulcer disease: a systematic review and network meta-analysis for randomized controlled trails [PDF]

Frontiers in Nutrition
Background and aimsVonoprazan, a novel acid suppressant, has been employed in the treatment of peptic ulcer disease in recent years. However, the efficacy and safety of vonoprazan versus proton-pump inhibitors remains controversial.
Lidi Tian, Dan Xiang, Feili Yue, Runjie Li, Youping Zhou   +4 more
doaj   +2 more sources

Treatment of Digital Ulcers and Reflux Oesophagitis in a Patient with Systemic Sclerosis: Increased Risk of Hepatotoxicity due to a Potential Drug-drug Interaction Between Bosentan and Vonoprazan

Acta Dermato-Venereologica, 2021
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Ryoko Kimura, Kazunari Sugita, Takaaki Sugihara, Hajime Isomoto, Osamu Yamamoto   +4 more
doaj   +1 more source

Lansoprazole for persistent throat symptoms in secondary care: the TOPPITS RCT

Health Technology Assessment, 2021
Background: Persistent throat symptoms are commonly attributed to ‘laryngopharyngeal reflux’. Despite a limited evidence base, these symptoms are increasingly being treated in primary care with proton pump inhibitors.
Janet A Wilson, Deborah D Stocken, Gillian C Watson, Tony Fouweather, Julian McGlashan, Kenneth MacKenzie, Paul Carding, Yakubu Karagama, Meredydd Harries, Stephen Ball, Sadie Khwaja, Declan Costello, Ruth Wood, Jan Lecouturier, James O’Hara   +14 more
doaj   +1 more source

PERBEDAAN SKOR RSI PENDERITA LARYNGOPHARYNGEAL REFLUX YANG MENDAPAT OMEPRZOLE DAN LANSOPRAZOLE

Jurnal Kedokteran Diponegoro, 2018
Latar Belakang : Laryngopharyngeal Reflux (LPR) adalah hasil aliran balik isi lambung ke laring faring yang menyebabkan cedera mukosa laring dan faring. Reflux Symptom Index (RSI) digunakan sebagai diagnosis dan evaluasi terapi LPR.
Sri Endah Eka Putri, Willy Yusmawan, Kanti Yunika   +2 more
doaj   +1 more source

Effectiveness of ranitidine bismuth citrate and proton pump inhibitor based triple therapies of Helicobacter pylori in Turkey [PDF]

Libyan Journal of Medicine, 2011
Background : Helicobacter pylori infection is the main cause of gastritis, gastroduodenal ulcer disease, MALT lymphoma, and adenocarcinoma of the stomach. The reported prevalence of H. pylori in the adult population in Turkey is 67.6%–81.3%.
Mustafa Iscan, Feriha Oz, Huseyin Alkim
doaj   +1 more source

Development of a Multifunctional Oral Dosage Form via Integration of Solid Dispersion Technology with a Black Seed Oil-Based Self-Nanoemulsifying Drug Delivery System

Biomedicines, 2023
Lansoprazole (LZP) is used to treat acid-related gastrointestinal disorders; however, its low aqueous solubility limits its oral absorption. Black seed oil (BSO) has gastroprotective effects, making it a promising addition to gastric treatment regimens ...
Abdelrahman Y. Sherif, Ahmad Abdul-Wahhab Shahba   +1 more
doaj   +1 more source

Pharmacodynamics and Pharmacokinetics of a New Type of Compound Lansoprazole Capsule in Gastric Ulcer Rats and Beagle Dogs: Importance of Adjusting Oxidative Stress and Inflammation

Pharmaceutics, 2019
: The aim of this study was to investigate the pharmacodynamics and pharmacokinetics of a new type of compound lansoprazole capsule in gastric ulcer rats and beagle dogs in order to confirm whether it is more effective in treating gastric ulcers and its ...
Binbin Wei, Yan Wang, Huizhe Wu, Mingyan Liu, Weifan Yao, Minjie Wei   +5 more
doaj   +1 more source