Results 91 to 100 of about 631,512 (303)

Toward a compact fibered squeezing parametric source

, 2018
In this work, we investigate three different compact fibered systems generating vacuum squeezing that involve optical cavities limited by the end surface of a fiber and by a curved mirror and containing a thin parametric crystal.
Brieussel, Alexandre, Fabre, Claude, Joos, Maxime, Ott, Konstantin, Treps, Nicolas   +4 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

High-Power Emission via Large-Area VCSELs With Single High-Order Mode Operation

IEEE Photonics Journal
In this work we investigate patterned large-active area AlGaAs vertical-cavity surface-emitting lasers (VCSELs) targeting high-power single-transverse-mode emission.
Valerio Torrelli, Alberto Gullino, Alberto Tibaldi, Francesco Bertazzi, Michele Goano, Pierluigi Debernardi   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Advances in Silica-Based Large Mode Area and Polarization-Maintaining Photonic Crystal Fiber Research. [PDF]

Materials (Basel), 2022
Ma Y, Wan R, Li S, Yang L, Wang P.
europepmc   +1 more source

Three-color femtosecond source for simultaneous excitation of three fluorescent proteins in two-photon fluorescence microscopy [PDF]

, 2012
We demonstrate a fiber-based, three-color femtosecond source for simultaneous imaging of three fluorescent proteins (FPs) using two-photon fluorescence microscopy (2PM).
Horton, Nicholas G., Lin, Charles P., Liu, Tzu-Ming, Wang, Ke, Wu, Juwell, Xu, Chris   +5 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

High power femtosecond chirped pulse amplification in large mode area photonic bandgap Bragg fibers

, 2011
International audienceWe report on high power amplification of femtosecond pulses in 40-μm core diameter Yb-doped photonic bandgap Bragg fibers. The robustness to bending and transverse spatial behavior of these fibers is analyzed through simulations ...
Daniault, Louis, Druon, Frédéric, Février, Sébastien, Gaponov, Dmitry, Georges, Patrick, Hanna, Marc, Likhachev, M.E., Roy, Philippe, Salganskii, M.Y., Yashkov, M.V.   +9 more
core   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source