Results 91 to 100 of about 424,562 (307)

A Numerical Study of Galaxy Formation and the Large Scale Structure of the Universe [PDF]

, 1993
K. Yamashita
openalex   +2 more sources

A Parameter-masked Mock Data Challenge for Beyond-two-point Galaxy Clustering Statistics

The Astrophysical Journal
The past few years have seen the emergence of a wide array of novel techniques for analyzing high-precision data from upcoming galaxy surveys, which aim to extend the statistical analysis of galaxy clustering data beyond the linear regime and the ...
The Beyond-2pt Collaboration, Elisabeth Krause, Yosuke Kobayashi, Andrés N. Salcedo, Mikhail M. Ivanov, Tom Abel, Kazuyuki Akitsu, Raul E. Angulo, Giovanni Cabass, Sofia Contarini, Carolina Cuesta-Lazaro, ChangHoon Hahn, Nico Hamaus, Donghui Jeong, Chirag Modi, Nhat-Minh Nguyen, Takahiro Nishimichi, Enrique Paillas, Marcos Pellejero Ibañez, Oliver H. E. Philcox, Alice Pisani, Fabian Schmidt, Satoshi Tanaka, Giovanni Verza, Sihan Yuan, Matteo Zennaro   +25 more
doaj   +1 more source

Stabilization of Large Scale Structure by Adhesive Gravitational Clustering [PDF]

, 1999
The interplay between gravitational and dispersive forces in a multi-streamed medium leads to an effect which is exposed in the present note as the genuine driving force of stabilization of large-scale structure. The conception of `adhesive gravitational
Buchert, Thomas
core   +3 more sources

Cosmological evolution of the gravitational entropy of the large-scale structure

, 2015
We consider the entropy associated with the large-scale structure of the Universe in the linear regime, where the Universe can be described by a perturbed Friedmann-Lema\^itre spacetime. In particular, we compare two different definitions proposed in the
Clarkson, Chris, Marozzi, Giovanni, Umeh, Obinna, Uzan, Jean-Philippe   +3 more
core   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Debiasing with Diffusion: Probabilistic Reconstruction of Dark Matter Fields from Galaxies with CAMELS

The Astrophysical Journal
Galaxies are biased tracers of the underlying cosmic web, which is dominated by dark matter (DM) components that cannot be directly observed. Galaxy formation simulations can be used to study the relationship between DM density fields and galaxy ...
Victoria Ono, Core Francisco Park, Nayantara Mudur, Yueying Ni, Carolina Cuesta-Lazaro, Francisco Villaescusa-Navarro   +5 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source