Results 91 to 100 of about 430,537 (306)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

AI-powered Reconstruction of Dark Matter Velocity Fields from Redshift-space Halo Distribution

open access: yesThe Astrophysical Journal
We propose a UNet-based deep learning model to reconstruct the real-space dark matter (DM) velocity field from the redshift-space distribution of sparse DM halos.
Xu Xiao   +8 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

The large scale structure of the universe

open access: yesNuclear Physics B, 1985
Abstract Observational data on galaxies and clusters of galaxies are reviewed in the context of how they relate to the large scale structure of the Universe. Various methods of interpreting these data are discussed.
openaire   +1 more source

Could the electroweak scale be linked to the large scale structure of the Universe? [PDF]

open access: yes
We study a model where the domain walls are generated through a cosmological phase transition involving a scalar field. We assume the existence of a coupling between the scalar field and dark matter and show that the interaction between domain walls and ...
Chakravorty, Alak   +1 more
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Large Scale Self-Similar Skeletal Structure of the Universe [PDF]

open access: yesAIP Conference Proceedings, 2006
An analysis of the redshift maps of galaxies and quasars has revealed large-scale self-similar skeletal structures of the Universe of the same topology which had been found earlier in a wide range of phenomena, spatial scales and environments. The "cartwheel" type of structure with diameter ~ 1.5 10^27 cm is discovered in this analysis by means of the ...
openaire   +2 more sources

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