Results 61 to 70 of about 5,772,324 (338)

Low spatial frequency laser-induced periodic surface structures in fused silica inscribed by widely tunable femtosecond laser pulses

Scientific Reports, 2022
The formation and evolution of laser-induced periodic surface structures in fused silica under irradiation of widely tunable (in the 1–3  $$\upmu$$ μ m range) linearly polarized femtosecond (200 fs) pulses was studied experimentally.
Marius Navickas, Robertas Grigutis, Vytautas Jukna, Gintaras Tamošauskas, Audrius Dubietis   +4 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Efficient injection of radiation-pressure-accelerated sub-relativistic protons into laser wakefield acceleration based on 10 PW lasers

, 2018
We propose a hybrid laser-driven ion acceleration scheme using a combination target of a solid foil and a density-tailored background plasma. In the first stage, a sub-relativistic proton beam can be generated by the radiation pressure acceleration in ...
Chen, M., He, M. Q., Li, Y. T., Liu, M., Sheng, Z. M., Wang, H. C., Weng, S. M., Zhang, J., Zhao, Q.   +8 more
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Real-time optoacoustic temperature determination on cell cultures during heat exposure: a feasibility study

International Journal of Hyperthermia, 2019
Objective/Purpose: In order to study the effects of hyperthermia and other temperature-related effects on cells and tissues, determining the precise time/temperature course is crucial.
Yoko Miura, Eric Seifert, Josua Rehra, Katharina Kern, Dirk Theisen-Kunde, Michael Denton, Ralf Brinkmann   +6 more
doaj   +1 more source

Engineering nanoparticle features to tune Rayleigh scattering in nanoparticles-doped optical fibers

Scientific Reports, 2021
Rayleigh scattering enhanced nanoparticles-doped optical fibers are highly promising for distributed sensing applications, however, the high optical losses induced by that scattering enhancement restrict considerably their sensing distance to few meters.
Victor Fuertes, Nicolas Grégoire, Philippe Labranche, Stéphane Gagnon, Ruohui Wang, Yannick Ledemi, Sophie LaRochelle, Younès Messaddeq   +7 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source