Results 91 to 100 of about 16,901 (224)
Advanced Science, Volume 12, Issue 44, November 27, 2025.Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen +9 more
wiley +1 more source
Die Rolle des Signalpeptids für die Reifung des Lassavirus Glykoproteins [PDF]
, 2004 Das Oberflächenglykoprotein des Lassavirus ist ein Typ 1-Membranprotein. Es wird als Vorläufer präGP-C synthetisiert und posttranslational mit N-Glykanen modifiziert.
Buckel, Wolfgang (Prof. Dr.) +1 more
core +1 more source
Partitioning Social and Spatial Drivers of Infection Risk
Ecology and Evolution, Volume 15, Issue 11, November 2025.Contact rates drive disease spread, yet are often oversimplified as uniform across individuals. Using data on Mastomys natalensis, we show that exposure to Morogoro virus is linked to spatial overlap with infected conspecifics, but not overall overlap, and that direct contact occurs with only a few individuals despite broad home range overlap ...
L. Kirkpatrick +4 more
wiley +1 more source
mRNA Vaccines: Current Applications and Future Directions
MedComm, Volume 6, Issue 11, November 2025.mRNA vaccines represent an innovative platform that leverages messenger RNA technology to direct cells to produce specific antigens, thereby eliciting an immune response. mRNA vaccines offer high programmability and significantly improved stability and immunogenicity through nucleotide modifications and delivery systems such as lipid nanoparticles ...
Jianmei Li +8 more
wiley +1 more source
Ecologic Traits Analysis for Identifying Rodent Hosts for Arenavirus and Hepacivirus in the Americas
Biotropica, Volume 57, Issue 6, November 2025.Over half of emerging human pathogens originate from wildlife, with rodents serving as key zoonotic hosts. This study used ecological trait‐based models to identify rodent traits associated with arenavirus and hepacivirus infections and detect potential host species across the Americas, our models achieve high predictive accuracy (AUC = 0.92–0.96).
María del Carmen Villalobos‐Segura +3 more
wiley +1 more source
Prevalence of Lassa virus among rodents trapped in three South-South States of Nigeria
Journal of Vector Borne Diseases, 2017 Background & objectives: Lassa fever has been endemic in Nigeria since 1969. The rodent Mastomys natalensis has been widely claimed to be the reservoir host of the Lassa virus.
D E Agbonlahor +12 more
doaj
We describe a strain of Lassa virus representing a putative new lineage that was isolated from a cluster of human infections with an epidemiologic link to Togo. This finding extends the known range of Lassa virus to Togo.2018UL1 TR000454/TR/NCATS NIH HHS/
core
From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways
Advanced Sensor Research, Volume 4, Issue 10, October 2025.Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley +1 more source
Therapeutic antibodies: current state and future trends--is a paradigm change coming soon? [PDF]
, 2008 Antibody-based therapeutics currently enjoy unprecedented success, growth in research and revenues, and recognition of their potential. It appears that the promise of the "magic bullet" has largely been realized.
Dimitrov, Dimiter S, Marks, James D
core +1 more source
Mastomys natalensis and Lassa Fever, West Africa
Emerging Infectious Diseases, 2006 PCR screening of 1,482 murid rodents from 13 genera caught in 18 different localities of Guinea, West Africa, showed Lassa virus infection only in molecularly typed Mastomys natalensis.
Emilie Lecompte +15 more
doaj +1 more source