Results 81 to 90 of about 1,049,804 (214)
Current research for a vaccine against Lassa hemorrhagic fever virus
Bryce M Warner,1 David Safronetz,2 Derek R Stein2 1Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada; 2Zoonotic Diseases and Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada ...
Safronetz D, Warner BM, Stein DR
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Lassa virus causes hemorrhagic Lassa fever in humans, while the related Old World arenaviruses Mopeia, Morogoro, and Mobala are supposedly apathogenic to humans and cause only inapparent infection in non-human primates.
Toni Rieger +2 more
doaj +1 more source
Identifizierung unbekannter Funktionen im Lassa-Virus L-Protein
The central domain of the 200-kDa Lassa virus L protein is a putative RNA-dependent RNA polymerase. N- and C-terminal domains may harbor enzymatic functions important for viral mRNA synthesis, including capping enzymes or cap-snatching endoribonucleases.
Lelke, Michaela
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Rodent control strategies and Lassa virus: some unexpected effects in Guinea, West Africa
The Natal multimammate mouse (Mastomys natalensis) is the host of Lassa mammarenavirus, causing Lassa haemorrhagic fever in West Africa. As there is currently no operational vaccine and therapeutic drugs are limited, we explored rodent control as an ...
Joachim Mariën +9 more
doaj +1 more source
Lassa fever is an acute viral illness that occurs in west Africa. The illness was discovered in 1969 when two missionary nurses died in Nigeria. The virus is named after the town in Nigeria where the first cases occurred. The virus, a member of the virus
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Summary: Background: Lassa fever vaccine trials are hampered by knowledge gaps on disease incidence, at-risk populations, sequelae, and transmission risks.
Abdel Mecit Dicko Issifou +167 more
doaj +1 more source
This data includes weekly cases of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents, specifically covering Lassa virus, Viral hemorrhagic fevers cases.
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CD4+ and CD8+ T cells are not the main driver of Lassa fever pathogenesis in macaques
Empirical data from survivors of Lassa fever and experimental disease modeling efforts, particularly those using mouse models, are at odds with respect to T cell–mediated pathogenesis.
Jérémie Prévost +13 more
doaj +1 more source
This data includes weekly cases of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents, specifically covering Lassa virus, Viral hemorrhagic fevers cases.
core
This data includes weekly cases of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents, specifically covering Lassa virus, Viral hemorrhagic fevers cases.
core

