Results 121 to 130 of about 8,755 (175)

Identification of residues in Lassa virus glycoprotein 1 involved in receptor switch. [PDF]

Virol Sin
Guo J, Wan Y, Liu Y, Jia X, Dong S, Xiao G, Wang W.   +6 more
europepmc   +1 more source

Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials. [PDF]

EBioMedicine
Cooper CL, Morrow G, Yuan M, Postler TS, Neal ML, Cross RW, Woolsey C, Agans KN, Borisevich V, McNamara RP, Atyeo C, Roy V, Germosen D, Hou F, Li SL, Reiserova L, Choi Y, Wilson A, Wagner D, Wallace-Selman O, Carpov A, Geng F, Frederick DJ, DeStefano J, Ercolini AM, Enriquez AS, Hastie KM, Ramos da Silva S, Sayeed E, Coleman JW, Kilianski A, Alter G, Saphire EO, Aitchison JD, Geisbert TW, Gupta SB, Feinberg MB, Parks CL.   +37 more
europepmc   +1 more source

Scaling Lassa Virus Dynamics within Anthropogenic Ecosystems (SCAPES) study: a mixed-methods observational cohort study of humans, rodents, and landscapes in Nigeria

Friant S, Simons D, Bjornstad O, Gibb R, Harden C, Imirzian N, Jones K, Smith A, Thompson K, Meremikwu M, Moses L, Redding D.   +11 more
europepmc   +1 more source

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Lassa Virus

Critical Reviews in Clinical Laboratory Sciences, 2004
Lassa virus is a RNA virus belonging to the family of Arenaviridae. It was discovered as the causative agent of a hemorrhagic fever--Lassa fever--about 30 years ago. Lassa fever is endemic in West Africa and is estimated to affect some 100,000 people annually. Great progress in the understanding of the life cycle of arenaviruses, including Lassa virus,
Stephan GÜNTHER
exaly   +3 more sources

Lassa Virus Infection: a Summary for Clinicians

International Journal of Infectious Diseases, 2022
This summary on Lassa virus (LASV) infection and Lassa fever disease (LF) was developed from a clinical perspective to provide clinicians with a condensed, accessible understanding of the current literature. The information provided highlights pathogenesis, clinical features, and diagnostics emphasizing therapies and vaccines that have demonstrated ...
Jared Evans, Richard Davey, Aneesh Mehta   +2 more
exaly   +4 more sources

Phylogeography of Lassa Virus in Nigeria [PDF]

Journal of Virology, 2019
Lassa virus is the causative agent of Lassa fever, a viral hemorrhagic fever with a case fatality rate of approximately 30% in Africa. Previous studies disclosed a geographical pattern in the distribution of Lassa virus strains and a westward movement of the virus across West Africa during evolution.
Ekaete Tobin, Danny Asogun, Sylvanus Akhalufo Okogbenin   +2 more
exaly   +5 more sources

Lassa Virus Genetics

2020
In a pattern repeated across a range of ecological niches, arenaviruses have evolved a compact four-gene genome to orchestrate a complex life cycle in a narrow range of susceptible hosts. A number of mammalian arenaviruses cross-infect humans, often causing a life-threatening viral hemorrhagic fever.
Raphaëlle, Klitting, Samar B, Mehta, Judith U, Oguzie, Paul E, Oluniyi, Matthias G, Pauthner, Katherine J, Siddle, Kristian G, Andersen, Christian T, Happi, Pardis C, Sabeti   +8 more
openaire   +2 more sources

Ecology of Lassa Virus

2020
Individuals living in endemic hotspots of Lassa fever have recurrent exposure to Lassa virus (LASV) via spillover from the primary host reservoir Mastomys natalensis. Despite M. natalensis being broadly distributed across sub-Saharan Africa, Lassa fever is only found in West Africa. In recent years, new LASV reservoirs have been identified.
Allison R, Smither, Antoinette R, Bell-Kareem   +1 more
openaire   +2 more sources

Lassa Virus Countermeasures

2022
Lassa Fever (LF) is a viral hemorrhagic fever endemic in West Africa. LF begins with flu-like symptoms that are difficult to distinguish from other common endemic diseases such as malaria, dengue, and yellow fever making it hard to diagnose clinically.
openaire   +2 more sources