Results 71 to 80 of about 178,686 (262)

A uniform isotopic and chemical signature of dust exported from Patagonia: Rock sources and occurrence in southern environments [PDF]

, 2007
Patagonia is considered to be the most important source of dust from South America that is deposited in surrounding areas, and we present here a systematic Sr and Nd isotopic study of sediment currently being exported.
Brunet, Frédéric, Depetris, Pedro J., Gaiero, Diego M., Probst, Jean-Luc   +3 more
core   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

New information on the Havelte Group site Ahrenshöft LA 58 D (Nordfriesland, Germany) - Preliminary results of the 2008 fieldwork [PDF]

, 2010
Late Glacial processes of human colonisation, adaptation and development represent a large field of study with a wide range of approaches. With respect to the archaeological succession from the classic Hamburgian to the Havelte Group, studies on the ...
Clausen, I., Housley, R. A., Miller, C. E., Riede, F., Usinger, H., Weber, M.-J.   +5 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The deglaciation of the mountains of Mexico and Central America

Cuadernos de Investigación Geográfica, 2017
The last deglaciation is an interval of marked changes in the climate system. The records of glaciation of tropical mountains offer unique opportunities to assess the timing of changes and the sensitivity of tropical climates to global and regional ...
L. Vázquez-Selem, M.S. Lachniet
doaj   +1 more source

A Cenozoic-style scenario for the end-Ordovician glaciation [PDF]

, 2014
The end-Ordovician was an enigmatic interval in the Phanerozoic, known for massive glaciation potentially at elevated CO2 levels, biogeochemical cycle disruptions recorded as large isotope anomalies and a devastating extinction event.
Achab, A, Asselin, E, Dabard, MP, Desrochers, A, Farley, C, Ghienne, JF, LOI, ALFREDO, Paris, F, Vandenbroucke, TRA, Veizer, J., Wickson, S   +10 more
core   +8 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Paleoenvironment conditions of the bottom sediment formation in the small lake depressions on the Pomorsky coast of the White Sea

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2015
New lithological, palinological and chronological data obtained through the study of bottom sediments from four small lake depressions on the Pomor Coast, Onega Bay, White Sea are presented.
Vasili Kolka, Olga Korsakova, Nadezhda Lavrova   +2 more
doaj   +1 more source

Late-Glacial to Late-holocene Shifts in Global Precipitation Delta(sup 18)O [PDF]

Reconstructions of Quaternary climate are often based on the isotopic content of paleo-precipitation preserved in proxy records. While many paleo-precipitation isotope records are available, few studies have synthesized these dispersed records to explore
Cendon, D.I., Fawcett, P.J., Galewsky, J., Gleeson, T., Jasechko, S., Lechler, A., LeGrande, A. N., Pausata, F.S.R., Risi, C., Sharp, Z. D., Welker, J. M., Werner, M., Yoshimura, K.   +12 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source