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Symposium 6: HLA and Non-HLA genetic predisposition
Symposium 6: Autoimmune diabetes: heterogeneity in its clinical presentations HLA and Non-HLA genetic predisposition Type 1 diabetes is a multifactorial autoimmune disease.
Gloria Cerrone
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Background. Latent autoimmune diabetes in adults (LADA) is a heterogeneous type of diabetes mellitus (DM) that combines symptoms of type 1 (T1DM) and type 2 diabetes mellitus (T2DM).
I.O. Tsaryk, N.V. Pashkovska
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Innate immunity in latent autoimmune diabetes in adults
Abstract Latent autoimmune diabetes in adults (LADA) is an autoimmune disease that shares some genetic, immunological and clinical features with both type 1 diabetes and type 2 diabetes. Immune cells including CD4 + T cells, CD8 + T ...
Juan Huang +4 more
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The role of cytokines in the pathogenesis of autoimmune diabetes, immune intervention issues
The review devotes to studying the role of cytokines in development of autoimmune diabetes mellitus, latent autoimmune diabetes in adults included. Therapeutic approaches to prevent the loss of endogenous insulin secretion are discussed.
Ye. B. Kravets +4 more
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Latent autoimmune diabetes in adults
Latent Autoimmune Diabetes in Adults (LADA) is the term used to describe adults who have a slowly progressive form of diabetes mellitus (DM) of autoimmune etiology, but that may be treated initially without insulin. Although it shares some immunological and genetic aspects with type 1 DM, it affects an age group that is typically affected by type 2 DM.
Felipe, Pollak, Tatiana, Vásquez
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The role of cholecalciferol deficiency in the development of latent autoimmune diabetes in adults
Background. Recently, a lot of information has appeared on the role of cholecalciferol deficiency in the development of the mechanisms of classical types of diabetes mellitus (DM) and its complications.
I.O. Tsaryk, N.V. Pashkovska
doaj +1 more source
Background. Latent autoimmune diabetes in youth (LADY) is underdiagnosed form of autoimmune diabetes that combines features of type 1 (T1DM) and type 2 diabetes mellitus (T2DM). In contrast to classical T1DM, LADY is characterized by a slowly progressive
N. Pashkovska, I. Tsaryk
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Background In adulthood, autoimmune diabetes can present as non-insulin-requiring diabetes, termed as ‘latent autoimmune diabetes in adults’ (LADA). In this study, we investigated established type 1 diabetes (T1D) and type 2 diabetes (T2D) genetic loci ...
Rajashree Mishra +16 more
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We present a case report of a 40-year-old Caucasian man who was diagnosed with type 2 diabetes mellitus at the age of 27. In his case, the patient took oral hypoglycemic drugs for 6 months, but then insulin therapy was started because glycemic goals were
A. V. Vetrova +2 more
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Interventions for latent autoimmune diabetes (LADA) in adults [PDF]
Latent autoimmune diabetes in adults (LADA) is a slowly developing type 1 diabetes.To compare interventions used for LADA.Studies were obtained from searches of electronic databases, supplemented by handsearches, conference proceedings and consultation with experts. Date of last search was December 2010.Randomised controlled trials (RCT) and controlled
S, Brophy +4 more
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