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Identification of immune phenotypes and diagnostic biomarkers in active and latent tuberculosis infections. [PDF]
Shao T, Yang L, Wu G, Lu X, Zheng R.
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Tuberculosis – eliminating the latent killer
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Redefining Latent Tuberculosis
Future Microbiology, 2011TB remains a public health problem worldwide, in part due to latent TB infection that serves as a global reservoir of potential disease. In the 20th century, the natural history of TB was defined by clinical symptoms, the tuberculin skin test and chest x-ray.
Saranya, Sridhar +2 more
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Eliminating latent tuberculosis
Trends in Microbiology, 2009Tuberculosis is recognized as the world's leading bacterial cause of death. Yet 95% of infection is believed to exist in an asymptomatic 'latent' form that is defined not by the identification of bacteria, but by the host immune response in the form of reactivity to tuberculosis proteins in the tuberculin skin test.
Douglas B, Young +2 more
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Seminars in Respiratory and Critical Care Medicine, 2004
Latent tuberculosis infection (LTBI) is a clinical condition characterized by a positive tuberculin skin test in the absence of clinical or radiological signs of active tuberculosis disease. It has been estimated that one third of the world's population is latently infected with Mycobacterium tuberculosis and serves as an enormous reservoir for future ...
Eric, Nuermberger +2 more
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Latent tuberculosis infection (LTBI) is a clinical condition characterized by a positive tuberculin skin test in the absence of clinical or radiological signs of active tuberculosis disease. It has been estimated that one third of the world's population is latently infected with Mycobacterium tuberculosis and serves as an enormous reservoir for future ...
Eric, Nuermberger +2 more
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Latent Mycobacterium tuberculosis Infection
New England Journal of Medicine, 2015The natural history of tuberculosis begins with the inhalation of Mycobacterium tuberculosis organisms; a period of bacterial replication and dissemination ensues, followed by immunologic containment of viable bacilli. The result of this process is asymptomatic latent tuberculosis infection, which is defined as a state of persistent bacterial viability,
Getahun, Haileyesus +3 more
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