Results 31 to 40 of about 3,405 (181)

Tuberculosis Infection and Latent Tuberculosis

open access: yesTuberculosis and Respiratory Diseases, 2016
Active tuberculosis (TB) has a greater burden of TB bacilli than latent TB and acts as an infection source for contacts. Latent tuberculosis infection (LTBI) is the state in which humans are infected with Mycobacterium tuberculosis without any clinical symptoms, radiological abnormality, or microbiological evidence.
openaire   +2 more sources

The ongoing challenge of latent tuberculosis [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2014
The global health community has set itself the task of eliminating tuberculosis (TB) as a public health problem by 2050. Although progress has been made in global TB control, the current decline in incidence of 2% yr−1is far from the rate needed to achieve this.
Esmail, H   +3 more
openaire   +3 more sources

Prevalence of latent tuberculosis in homeless persons: A single-centre cross-sectional study, Germany.

open access: yesPLoS ONE, 2019
PURPOSE:Homeless persons have a high risk for tuberculosis. The prevalence of latent tuberculosis infection and the risk for a progression to active tuberculosis is higher in the homeless than in the general population.
Friederike von Streit   +5 more
doaj   +1 more source

Immunological aspects of host–pathogen crosstalk in the co-pathogenesis of diabetes and latent tuberculosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionDiabetes is a potent risk factor for the activation of latent tuberculosis and worsens the tuberculosis (TB) treatment outcome. The major reason for mortality and morbidity in diabetic patients is due to their increased susceptibility to TB ...
Arpana Verma   +8 more
doaj   +1 more source

Impact of Latent Tuberculosis on Diabetes

open access: yesThe Journal of Infectious Diseases, 2022
Abstract While an increased risk of active and latent tuberculosis infection (LTBI) in people with type-2 diabetes (DM) has been demonstrated, it is less well characterized whether LTBI is associated with an increased risk of developing DM.
Burcu Tepekule   +62 more
openaire   +3 more sources

Treatment of latent tuberculosis infection [PDF]

open access: yesTherapeutic Advances in Respiratory Disease, 2013
Treatment of latent tuberculosis (TB) infection is an important component of TB control programs in both high- and low-prevalence countries. Clinical trials of treatment of latent TB conducted over several decades have demonstrated that preventive treatment can reduce the risk of developing active TB up to 90%.
Madhavi J. Parekh, Neil W. Schluger
openaire   +5 more sources

Safety of Interleukin Inhibitors in Psoriatic Patients with Latent Tuberculosis Infection Without Chemoprophylaxis: A Systematic Review

open access: yesActa Dermato-Venereologica
Current guidelines recommend psoriatic patients with latent tuberculosis infection undergo chemoprophylaxis prior to initiating any biologic. However, clinical studies indicate that interleukin (IL) inhibitors may not increase the risk of tuberculosis ...
Jiaying Li   +5 more
doaj   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

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