Results 31 to 40 of about 107,291 (259)
BackgroundThe majority of tuberculosis in migrants to Canada occurs due to reactivation of latent TB infection. Risk of tuberculosis in those with latent tuberculosis infection can be significantly reduced with treatment.
Jonathon R Campbell +5 more
doaj +1 more source
Determinants of latent tuberculosis infection among nurses at public health centers in Indonesia
Background: The incidence of latent tuberculosis among healthcare workers, especially nurses, at public health centers in Indonesia has been increased. Therefore, factors related to the tuberculosis incidence need to be further investigated. Objective:
Meira Erawati, Megah Andriany
doaj +1 more source
Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. [PDF]
Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish panels of serum protein biomarkers representative of active TB patients and their household contacts who were either infected (LTBI)
Anibarro, L +11 more
core +2 more sources
Objective: This cohort study aimed to determine the prevalence and risk factors of latent tuberculosis infection among healthcare workers during the COVID-19 pandemic.
Mojgan Sehat +4 more
doaj +1 more source
Outlook for tuberculosis elimination in California: An individual-based stochastic model. [PDF]
RationaleAs part of the End TB Strategy, the World Health Organization calls for low-tuberculosis (TB) incidence settings to achieve pre-elimination (<10 cases per million) and elimination (<1 case per million) by 2035 and 2050, respectively. These
Barry, Pennan M +10 more
core +3 more sources
Objectives: To assess the degree to which Latent Tuberculosis exist among long–term inmates in jail. Study Design:Prospective Cohort Analytic Experimental Quantitative Data. Setting and Period: Jails at Bahawalpur between 2009-2010. Methods: Wemonitored the Mountex Test of prisoners within 48 to 72 h and those who were 10 mm or more were considered ...
JAVED IQBAL +2 more
openaire +2 more sources
The relative fitness of drug-resistant Mycobacterium tuberculosis: a modelling study of household transmission in Peru. [PDF]
The relative fitness of drug-resistant versus susceptible bacteria in an environment dictates resistance prevalence. Estimates for the relative fitness of resistant Mycobacterium tuberculosis (Mtb) strains are highly heterogeneous and mostly derived from
Friedland, JS +5 more
core +7 more sources
Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh +9 more
core +1 more source
Treatment of Latent Tuberculosis Infection [PDF]
The treatment of latent tuberculosis infection (LTBI) is an essential component of tuberculosis (TB) elimination in regions that have a low incidence of TB. However, the decision to treat individuals with LTBI must consider the limitations of current diagnostic tests for LTBI, the risk of developing active TB disease, the potential adverse effects from
Tang, Patrick, Johnston, James
openaire +4 more sources
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources

