Results 51 to 60 of about 61,450 (241)

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION

Медицинский вестник Юга России, 2015
Purpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people ...
L. A. Shovkun, I. M. Franchuk, Ye. D. Kampos, A. V. Konstantinova, O. V. Ilyina   +4 more
doaj   +1 more source

LATENT TUBERCULOSIS;

The Professional Medical Journal, 2012
Objectives: To assess the degree to which Latent Tuberculosis exist among long–term inmates in jail. Study Design:Prospective Cohort Analytic Experimental Quantitative Data. Setting and Period: Jails at Bahawalpur between 2009-2010. Methods: Wemonitored the Mountex Test of prisoners within 48 to 72 h and those who were 10 mm or more were considered ...
JAVED IQBAL, ALTAF HUSSAIN MALIK, Aftab JAMIL   +2 more
openaire   +2 more sources

A Mouse Model for Latent Tuberculosis [PDF]

Scandinavian Journal of Infectious Diseases, 1998
The aim of the study was to establish a reproducible murine model for latent tuberculosis. We propose an operational definition of latent murine tuberculosis as a stable Mycobacterium-tuberculosis count in lungs and spleens without clinical signs or obvious histopathological changes in the lungs over a long period of time and without spontaneous ...
Phyu, S., Mustafa, Tehmina, Hofstad, T., Nilsen, Rune, Fosse, R., Bjune, Gunnar Aksel   +5 more
openaire   +4 more sources

The human immune response to tuberculosis and its treatment: a view from the blood. [PDF]

, 2015
The immune response upon infection with the pathogen Mycobacterium tuberculosis is poorly understood, hampering the discovery of new treatments and the improvements in diagnosis.
van Helden, Paul, van Helden, P., Cliff, Jacqueline M, Kaufmann, Stefan HE, O'Garra, Anne, Kaufmann, S., McShane, H., O'Garra, A., Cliff, J., McShane, Helen   +9 more
core   +1 more source

Prevalence and Risk Factors of Latent Tuberculosis Infection (LTBI) at Madura Boarding School as a High-Risk Congregate Setting

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Introduction: Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a highly contagious airborne disease. High-risk environments with frequent close interactions contribute to the spread of TB.
Muhammad Arif Ananto, Retno Asih Setyoningrum, Pudji Lestari   +2 more
doaj   +1 more source

Various Forms of Tuberculosis in Patients with Inflammatory Bowel Diseases Treated with Biological Agents

International Journal of Inflammation, 2021
Although there are undeniable advantages of treatment of the inflammatory bowel diseases, Crohn’s disease, and ulcerative colitis, with biological agents, the increased susceptibility to tuberculosis should not be ignored.
Adam Krusiński, Anna Grzywa-Celińska, Katarzyna Szewczyk, Luiza Grzycka-Kowalczyk, Justyna Emeryk-Maksymiuk, Janusz Milanowski   +5 more
doaj   +1 more source

Screening for tuberculosis of patients with HIV-infection. New possibilities

Acta Biomedica Scientifica, 2022
Background. Tuberculosis associated with HIV infection is becoming almost a new disease, where not only new approaches to treatment are being formed, but there is also a need to improve the quality and search for new means of early diagnosis of ...
E. A. Borodulina, D. A. Kudlay, A. N. Kuznetsova   +2 more
doaj   +1 more source

Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in mycobacterium tuberculosis–infected individuals [PDF]

, 2009
Copyright © 2009 by the American Thoracic Society.Rationale: An effective new tuberculosis (TB) vaccine regimen must be safe in individuals with latent TB infection (LTBI) and is a priority for global health care.
Beveridge, NER, Alder, N, Davies, RJ, Minassian, A, Hill, Adrian, Beveridge, NE, Gleeson, FV, Pasvol, G, Hill, AVS, Mcshane, Helen, Davies, RJO, Van Wijgerden, J, Gleeson, Fergus, Poulton, I, Sander, CR, Pathan, AA, McShane, H, Hill, AV   +17 more
core   +1 more source

Diagnostic accuracy of interferon-gamma-induced protein 10 for differentiating active tuberculosis from latent tuberculosis: A meta-analysis

Scientific Reports, 2019
Tuberculin skin test and interferon-gamma release assay are not good at differentiating active tuberculosis from latent tuberculosis. Interferon-gamma-induced protein 10 (IP-10) has been widely used to detect tuberculosis infection.
Xia Qiu, Ying Tang, Rong Zou, Yan Zeng, Yan Yue, Wenxing Li, Yi Qu, Dezhi Mu   +7 more
doaj   +1 more source