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Tuberculosis Infection and Latent Tuberculosis
Active tuberculosis (TB) has a greater burden of TB bacilli than latent TB and acts as an infection source for contacts. Latent tuberculosis infection (LTBI) is the state in which humans are infected with Mycobacterium tuberculosis without any clinical symptoms, radiological abnormality, or microbiological evidence.
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Screening for Latent Tuberculosis [PDF]
This JAMA Patient Page describes latent and active tuberculosis and discusses the pros and cons of screening for latent tuberculosis.
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Isoniazid use, effectiveness, and safety for treatment of latent tuberculosis infection: a systematic review [PDF]
Background: The treatment strategy for latent tuberculosis infection is to reduce the number of tuberculosis cases and consequently reduce the transmission of pathogenic bacteria. This study aimed to determine the safety, effectiveness, and adherence of
Bárbara Manuella Cardoso Sodré-Alves +4 more
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Tuberculosis and COVID-19 Dually Affect Human Th17 Cell Immune Response
COVID-19 infection not only profoundly impacts the detection of tuberculosis infection (Tbc) but also affects modality in tuberculosis patient immune response.
Anna Starshinova +5 more
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Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales +12 more
wiley +1 more source
Two-Component Systems of Mycobacterium tuberculosis as potential targets for drug development [PDF]
Tuberculosis, caused by Mycobacterium tuberculosis, is a global health problem with approximately two million deaths every year. Furthermore, up to one-third of the world population is infected with latent form of this bacterium.Existing anti ...
Marszalek, Marta +2 more
core
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Purpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people ...
L. A. Shovkun +4 more
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Although there are undeniable advantages of treatment of the inflammatory bowel diseases, Crohn’s disease, and ulcerative colitis, with biological agents, the increased susceptibility to tuberculosis should not be ignored.
Adam Krusiński +5 more
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Screening for tuberculosis of patients with HIV-infection. New possibilities
Background. Tuberculosis associated with HIV infection is becoming almost a new disease, where not only new approaches to treatment are being formed, but there is also a need to improve the quality and search for new means of early diagnosis of ...
E. A. Borodulina +2 more
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