Results 71 to 80 of about 2,066,293 (256)

Tuberculosis and COVID-19 Dually Affect Human Th17 Cell Immune Response

Biomedicines, 2023
COVID-19 infection not only profoundly impacts the detection of tuberculosis infection (Tbc) but also affects modality in tuberculosis patient immune response.
Anna Starshinova, Igor Kudryavtsev, Artem Rubinstein, Anna Malkova, Irina Dovgaluk, Dmitry Kudlay   +5 more
doaj   +1 more source

Latent Tuberculosis Infection Diagnosis and Treatment

, 2021
This book chapter provides an overview over the latent tuberculosis infection (LTBI) testing and treatment. It provides details of the currently available immunological diagnostic tests, as well as LTBI treatment, referring to the best available evidence
Alberto Matteelli, Altass, L, Matteelli, A, Judith Bruchfeld, Zenner, D, Lynn Altass, Dominik Zenner, Bruchfeld, J, Kunst, H, Heinke Kunst   +9 more
core   +1 more source

Pharmacokinetics of Rifapentine and Desacetyl Rifapentine in Maternal Plasma and Breast Milk & Infant Cord Blood and Plasma: A Model‐Based Analysis of Mother–Infant Pairs for Tuberculosis Prevention

Clinical Pharmacology &Therapeutics, EarlyView.
IMPAACT 2001 (NCT02651259) evaluated the safety and pharmacokinetics (PK) of once‐weekly isoniazid and rifapentine in pregnant and postpartum women for tuberculosis prevention. Rifapentine (RPT) and desacetyl rifapentine (desRPT) PK data were collected in maternal plasma, breast milk, infant cord blood, and infant plasma.
Priya Jayachandran, Jyoti S. Mathad, Nan Zhang, Paula Britto, Lubbe Wiesner, Grace Montepiedra, Jennifer Norman, Ellen Townley, Sarah Bradford, Sandesh Patil, Stephanie Popson, Tsungai Chipato, Vanessa Rouzier, Deborah Langat, Amphan Chalermchockcharoentkit, Amita Gupta, Kelly E. Dooley, Radojka Savic, on behalf of the IMPAACT 2001 Study Team   +18 more
wiley   +1 more source

Mycobacterium tuberculosis Dormancy: How to Fight a Hidden Danger

Microorganisms, 2022
Both latent and active TB infections are caused by a heterogeneous population of mycobacteria, which includes actively replicating and dormant bacilli in different proportions. Dormancy substantially affects M. tuberculosis drug tolerance and TB clinical
Elena G. Salina, Vadim Makarov
doaj   +1 more source

Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection.

Journal of Clinical Investigation, 2019
HIV is a major driver of Tuberculosis (TB) reactivation. Depletion of CD4+ T cells is assumed to be the basis behind TB reactivation in individuals with latent tuberculosis Infection (LTBI) co-infected with human immunodeficiency virus (HIV).
Allison N. Bucşan, Ayan Chatterjee, D. Singh, Taylor W. Foreman, Tae-Hyung Lee, Breanna M. Threeton, Melanie G. Kirkpatrick, Mushtaq Ahmed, Nadia A. Golden, X. Alvarez, J. Hoxie, S. Mehra, Jyothi Rengarajan, S. Khader, D. Kaushal   +14 more
semanticscholar   +1 more source

From patterns to predictions: a framework for the spatial epidemiology of wildlife diseases

Ecography, EarlyView.
Wildlife diseases pose a significant threat to biodiversity conservation, public health, and livestock. Spatial epidemiology provides a robust framework to understand disease dynamics and guide policy and management. However, the rapid proliferation of spatial methods has largely occurred in isolation across disciplines, leaving the field without a ...
Cesar Herraiz, Pelayo Acevedo
wiley   +1 more source

Prevalence and Risk Factors of Latent Tuberculosis Infection (LTBI) at Madura Boarding School as a High-Risk Congregate Setting

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Introduction: Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a highly contagious airborne disease. High-risk environments with frequent close interactions contribute to the spread of TB.
Muhammad Arif Ananto, Retno Asih Setyoningrum, Pudji Lestari   +2 more
doaj   +1 more source

INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION

Медицинский вестник Юга России, 2015
Purpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people ...
L. A. Shovkun, I. M. Franchuk, Ye. D. Kampos, A. V. Konstantinova, O. V. Ilyina   +4 more
doaj   +1 more source

Various Forms of Tuberculosis in Patients with Inflammatory Bowel Diseases Treated with Biological Agents

International Journal of Inflammation, 2021
Although there are undeniable advantages of treatment of the inflammatory bowel diseases, Crohn’s disease, and ulcerative colitis, with biological agents, the increased susceptibility to tuberculosis should not be ignored.
Adam Krusiński, Anna Grzywa-Celińska, Katarzyna Szewczyk, Luiza Grzycka-Kowalczyk, Justyna Emeryk-Maksymiuk, Janusz Milanowski   +5 more
doaj   +1 more source

Diagnosis and Management of Latent Tuberculosis Infection in Asia: Review of Current Status and Challenges.

International Journal of Infectious Diseases, 2019
Asia has the highest burden of tuberculosis (TB) and latent TB infection (LTBI) in the world. Optimizing the diagnosis and treatment of LTBI is one of the key strategies for achieving the WHO 'End TB' targets.
N. Paton, L. Borand, J. Benedicto, M. M. Kyi, A. Mahmud, M. Norazmi, N. Sharma, C. Chuchottaworn, Yi-Wen Huang, N. Kaswandani, Hoi Le Van, G. Lui, T. Mao   +12 more
semanticscholar   +1 more source