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TB Elimination: The Difference Between Latent TB Infection and TB Disease [PDF]

Tuberculosis (TB) is a disease caused by a germ called Mycobacterium tuberculosis that is spread from person to person through the air. TB usually affects the lungs, but it can also affect other parts of the body, such as the brain, the kidneys, or the ...

core   +2 more sources

Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages

mSphere, 2017
During tuberculosis, macrophages are critical for both pathogen survival and host immune activation. Since expression of particular cell surface markers reflects cell function, we used flow cytometry to measure the abundance of surface markers associated
Karim Lakehal, David Levine, Kathleen F. Kerr, Pooja Vir, Natalie Bruiners, Alfred Lardizabal, Maria Laura Gennaro, Richard Pine   +7 more
doaj   +1 more source

From Latent Tuberculosis Infection to Tuberculosis. News in Diagnosticsb (QuantiFERON-Plus) [PDF]

Polish Journal of Microbiology, 2017
It is estimated that one third of the world’s population have latent tuberculosis infection and that this is a significant reservoir for future tuberculosis cases. Most cases occur within two years following initial infection. The identification of
Dagmara I. Borkowska, Agnieszka M. Napiórkowska, Sylwia A. Brzezińska, Monika Kozińska, Anna T. Zabost, Ewa M. Augustynowicz-Kopeć   +5 more
doaj   +1 more source

Latent tuberculosis infection in patients with rheumatic diseases

Jornal Brasileiro de Pneumologia, 2019
Most people infected by Mycobacterium tuberculosis (Mtb) do not have any signs or disease symptoms, a condition known as latent tuberculosis infection (LTBI).
C. Anton, F. D. Machado, Jorge Mario Ahumada Ramirez, R. M. Bernardi, P. Palominos, C. Brenol, F. C. de Queiroz Mello, D. R. Silva   +7 more
semanticscholar   +1 more source

Determining Mycobacterium tuberculosis infection among BCG-immunised Ugandan children by T-SPOT.TB and tuberculin skin testing. [PDF]

, 2012
BACKGROUND: Children with latent tuberculosis infection (LTBI) represent a huge reservoir for future disease. We wished to determine Mycobacterium tuberculosis (M.tb) infection prevalence among BCG-immunised five-year-old children in Entebbe, Uganda, but
Webb, Emily L, Gyaviira Nkurunungi, Muhangi Lawrence, Cose Stephen, Joseph R Fitchett, Akurut, Hellen, Elliott Alison M., Kizito Dennison, Kizindo Robert, Muhangi, Lawrence, Swaib A Lule, Lawrence Muhangi, Alison M Elliott, Akurut Hellen, Hellen Akurut, Robert Kizindo, Sebina, Ismail, Cose, Stephen, Elliott, Alison M, Nkurunungi Gyaviira, Kizito, Dennison, Fitchett, Joseph R, Sebina Ismail, Kizindo, Robert, Emily L Webb, Webb Emily L., Lutangira Jimreeves E., Jimreeves E Lutangira, Lule Swaib A., Stephen Cose, Lule, Swaib A, Dennison Kizito, Fitchett Joseph R., Nkurunungi, Gyaviira, Lutangira, Jimreeves E, Ismail Sebina   +35 more
core   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Treatment of latent tuberculosis infection and tuberculosis disease [PDF]

In this module, you will learn about the principles of treating latent TB infection (LTBI) and TB disease. A person with LTBI is treated to prevent them from progressing to TB disease. Some people with LTBI are at very high risk of developing TB disease,

core   +2 more sources

The Prevalence of Latent Tuberculosis Infection and Smear Positive Pulmonary Tuberculosis in People with Household Close Contact with Tuberculosis in North of Iran

Iranian Journal of Medical Sciences, 2015
One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people
Mahmood Moosazadeh, Narges Khanjani, Mohammadreza Parsaee   +2 more
doaj  

Prevalence and risk factors of latent tuberculosis infection among health care workers in Malaysia

BMC Infectious Diseases, 2011
Background Health care workers are exposed to patients with tuberculosis and are at risk of nosocomial infection. The aim of this study was to determine the prevalence and factors associated with latent tuberculosis infection among health care workers in
Rampal Krishna, Rafiza Shaharudin, Tahir Aris   +2 more
doaj   +1 more source

Latent tuberculosis infection: An overview.

Canada communicable disease report = Releve des maladies transmissibles au Canada, 2017
Latent tuberculosis infection (LTBI) is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens without evidence of clinically manifested active tuberculosis (TB) disease.
S. Kiazyk, T. B. Ball
semanticscholar   +1 more source