Results 111 to 120 of about 54,559 (220)

Prevalence of Tuberculosis Infection by Interferon-Gamma Release Assay and Risk Factors Associated with Latent Tuberculosis Infection among Household Contacts of Pulmonary Tuberculosis Patients in Roi Et Province, Thailand

open access: yesJournal of Health Research
            Background: Tuberculosis remains a major global public health challenge. This study determined the prevalence of latent tuberculosis infection (LTBI) using the Interferon-Gamma Release Assay (IGRA) and identified associated risk factors among
Sakaren Lawong
doaj   +1 more source

Experiences of Integration of HIV, Hepatitis, and Sexually Transmitted Infection Services Across Different Countries Worldwide: A Scoping Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Integrating services for diseases appears to improve healthcare access and outcomes. This scoping review aimed to evaluate how different countries implement the integration of HIV, viral hepatitis, and sexually transmitted infection (STI) services.
Parya Jangipour Afshar   +7 more
wiley   +1 more source

Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz   +10 more
wiley   +1 more source

Early Local Treatment Delays Multiple Metastases in Non‐Small Cell Lung Cancer With Solitary Distant Metastasis: A Multicenter Retrospective Cohort Study

open access: yesMedComm, Volume 7, Issue 9, September 2026.
In NSCLC patients with solitary distant metastasis (SDM), early local treatment significantly delays the progression to multi‐metastasis by 14 months (HR = 0.55) compared to delayed or no treatment. This multicenter cohort study highlights SDM as an indolent state, emphasizing the critical time window for effective local intervention. .
Kang Miao   +10 more
wiley   +1 more source

Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi   +6 more
wiley   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao   +10 more
wiley   +1 more source

Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract In bacteria, DnaB replicative helicases are essential for unwinding genomic DNA to provide the single‐stranded templates required for replication. The recruitment of the hexameric DnaB helicase to the origin of replication is mediated by distinct mechanisms that rely on specialized factors known as helicase loaders. The DciA family of helicase
Daniele Mazzoletti   +8 more
wiley   +1 more source

Can Multidrug‐Resistant and Extensively Drug‐Resistant Tuberculosis be Treated More Successfully?

open access: yesPublic Health Challenges, Volume 5, Issue 3, September 2026.
Drug‐resistant cases of tuberculosis are increasing, complicating treatment strategies. Prior to the development of pharmacological agents, improving patient health at institutions called ‘sanatoria’ was a successful primary treatment. World Health Organization data combined with information from historical reports estimate that current treatments can ...
K. L. Holloway‐Kew, M. Henneberg
wiley   +1 more source

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