Results 41 to 50 of about 3,405 (181)

Mycobacterium tuberculosis Dormancy: How to Fight a Hidden Danger

Microorganisms, 2022
Both latent and active TB infections are caused by a heterogeneous population of mycobacteria, which includes actively replicating and dormant bacilli in different proportions. Dormancy substantially affects M. tuberculosis drug tolerance and TB clinical
Elena G. Salina, Vadim Makarov
doaj   +1 more source

Isoniazid use, effectiveness, and safety for treatment of latent tuberculosis infection: a systematic review [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Background: The treatment strategy for latent tuberculosis infection is to reduce the number of tuberculosis cases and consequently reduce the transmission of pathogenic bacteria. This study aimed to determine the safety, effectiveness, and adherence of
Bárbara Manuella Cardoso Sodré-Alves, Melina Mafra Toledo, Ivan Ricardo Zimmermann, Wildo Navegantes de Araújo, Noemia Urruth Leão Tavares   +4 more
doaj   +1 more source

Tuberculosis and COVID-19 Dually Affect Human Th17 Cell Immune Response

Biomedicines, 2023
COVID-19 infection not only profoundly impacts the detection of tuberculosis infection (Tbc) but also affects modality in tuberculosis patient immune response.
Anna Starshinova, Igor Kudryavtsev, Artem Rubinstein, Anna Malkova, Irina Dovgaluk, Dmitry Kudlay   +5 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION

Медицинский вестник Юга России, 2015
Purpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people ...
L. A. Shovkun, I. M. Franchuk, Ye. D. Kampos, A. V. Konstantinova, O. V. Ilyina   +4 more
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Diagnostic accuracy of interferon-gamma-induced protein 10 for differentiating active tuberculosis from latent tuberculosis: A meta-analysis

Scientific Reports, 2019
Tuberculin skin test and interferon-gamma release assay are not good at differentiating active tuberculosis from latent tuberculosis. Interferon-gamma-induced protein 10 (IP-10) has been widely used to detect tuberculosis infection.
Xia Qiu, Ying Tang, Rong Zou, Yan Zeng, Yan Yue, Wenxing Li, Yi Qu, Dezhi Mu   +7 more
doaj   +1 more source

Various Forms of Tuberculosis in Patients with Inflammatory Bowel Diseases Treated with Biological Agents

International Journal of Inflammation, 2021
Although there are undeniable advantages of treatment of the inflammatory bowel diseases, Crohn’s disease, and ulcerative colitis, with biological agents, the increased susceptibility to tuberculosis should not be ignored.
Adam Krusiński, Anna Grzywa-Celińska, Katarzyna Szewczyk, Luiza Grzycka-Kowalczyk, Justyna Emeryk-Maksymiuk, Janusz Milanowski   +5 more
doaj   +1 more source

Screening for tuberculosis of patients with HIV-infection. New possibilities

Acta Biomedica Scientifica, 2022
Background. Tuberculosis associated with HIV infection is becoming almost a new disease, where not only new approaches to treatment are being formed, but there is also a need to improve the quality and search for new means of early diagnosis of ...
E. A. Borodulina, D. A. Kudlay, A. N. Kuznetsova   +2 more
doaj   +1 more source

A Mouse Model for Latent Tuberculosis [PDF]

Scandinavian Journal of Infectious Diseases, 1998
The aim of the study was to establish a reproducible murine model for latent tuberculosis. We propose an operational definition of latent murine tuberculosis as a stable Mycobacterium-tuberculosis count in lungs and spleens without clinical signs or obvious histopathological changes in the lungs over a long period of time and without spontaneous ...
Phyu, S., Mustafa, Tehmina, Hofstad, T., Nilsen, Rune, Fosse, R., Bjune, Gunnar Aksel   +5 more
openaire   +4 more sources