Results 91 to 100 of about 226,651 (317)

In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]

, 2008
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD, Peter, S, Pulimood, AB, Rook, GWA   +3 more
core   +1 more source

Comparison of TST and IGRA in Diagnosis of Latent Tuberculosis Infection in a High TB-Burden Setting

PLoS ONE, 2017
Background There are currently two tests for diagnosing latent tuberculosis infection (LTBI); TST and IGRA. However, it is still unclear that which one of these tests performs better in high TB-burden settings.
Surendra K Sharma, R. Vashishtha, L. S. Chauhan, V. Sreenivas, D. Seth   +4 more
semanticscholar   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

The Prevalence of Latent Tuberculosis Infection and Smear Positive Pulmonary Tuberculosis in People with Household Close Contact with Tuberculosis in North of Iran

Iranian Journal of Medical Sciences, 2015
One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people
Mahmood Moosazadeh, Narges Khanjani, Mohammadreza Parsaee   +2 more
doaj  

Latent Tuberculosis Infection - Diagnosis and Treatment

Open Access Macedonian Journal of Medical Sciences, 2018
INTRODUCTION: Latent tuberculosis infection (LTBI) is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens without evidence of clinically manifested active tuberculosis (TB). Diagnosis and treatment for LTBI are important for TB, especially in high-risk populations.
Ilievska-Poposka, Biljana, Metodieva, Marija, Zakoska, Maja, Vragoterova, Cveta, Trajkov, Dejan   +4 more
openaire   +5 more sources

Guidance for programmatic management of latent tuberculosis infection in the European Union/European Economic Area

European Respiratory Journal, 2019
Worldwide efforts are being made to end tuberculosis (TB) by 2035 following the ambitions outlined in the World Health Organization (WHO) End TB strategy [1] and the United Nations Sustainable Development Goals [2].
S. Rosales-Klintz, J. Bruchfeld, W. Haas, E. Heldal, R. Houben, F. van Kessel, M. Mandelbaum, A. Matteelli, G. Migliori, Anouk M. Oordt-Speets, I. Solovič, M. Vašáková, S. Verver, S. D. de Vlas, M. Vonk Noordegraaf-Schouten, G. de Vries, D. Zenner, M. J. van der Werf   +17 more
semanticscholar   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Attenuation of toll-like receptor expression and function in latent tuberculosis by coexistent filarial infection with restoration following antifilarial chemotherapy. [PDF]

PLoS Neglected Tropical Diseases, 2009
Mycobacterium tuberculosis (Mtb) and filarial coinfection is highly prevalent, and the presence of filarial infections may regulate the Toll-like receptor (TLR)-dependent immune response needed to control Mtb infection.
Subash Babu, Sajid Q Bhat, N Pavan Kumar, R Anuradha, Paul Kumaran, P G Gopi, C Kolappan, V Kumaraswami, Thomas B Nutman   +8 more
doaj   +1 more source

A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]

, 2019
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D, Dowd, JB, Fletcher, H, Hayward, SE, Nellums, LB, Wurie, F   +5 more
core   +2 more sources

Inconsistent standard of care for tuberculosis screening and preventive therapy before initiating systemic psoriasis treatment

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Preventive tuberculosis (TB) therapy before initiating MTX or IL‐17/IL‐23/IL‐12/23p40 inhibitors for latent tuberculosis infection (LTBI) is supported by indirect evidence of TB reactivations with TNF inhibitors. However, direct evidence for MTX or IL‐17/IL‐23/IL‐12/23p40 inhibitors is limited.
Christoph Zeyen, Ruben Heuer, Brit Haecker, Tom Schaberg, Alexander Nast   +4 more
wiley   +1 more source