Results 101 to 110 of about 88,192 (248)

Two-Component Systems of Mycobacterium tuberculosis as potential targets for drug development [PDF]

, 2014
Tuberculosis, caused by Mycobacterium tuberculosis, is a global health problem with approximately two million deaths every year. Furthermore, up to one-third of the world population is infected with latent form of this bacterium.Existing anti ...
Marszalek, Marta, Pellicer, Teresa, Planas, Antoni   +2 more
core  

Managing latent tuberculosis infection and tuberculosis in children

Pulmonology, 2018
Tuberculosis (TB) is a major cause of childhood morbidity and mortality worldwide. The aim of this review is to describe the management of the child with TB and latent tuberculosis infection (LTBI). To develop this article, a working group reviewed relevant epidemiological and other scientific studies and established practices in conducting LBTI and TB
I. Carvalho, D. Goletti, S. Manga, D.R. Silva, D. Manissero, G. Migliori   +5 more
openaire   +4 more sources

Latent Neoehrlichia mikurensis Infections May Be Reactivated in Patients With B‐Cell Lymphomas Treated With Rituximab

Immunology, EarlyView.
Eight percent of this cohort of patients had a latent Neoehrlichia mikurensis infection. It was only the latently infected patients who had N. mikurensis‐specific T cells, not the matched B‐cell lymphoma patients without the infection. The T‐cell responses of latently infected patients included perforin‐expressing Th1 and CD8+ T cells that upregulated ...
Linda Wass, Catharina Lewerin, Daniel Jaén‐Luchoro, Christine Lingblom, Christine Wennerås   +4 more
wiley   +1 more source

The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. [PDF]

, 2014
BACKGROUND: Unlike other respiratory infections, tuberculosis diagnoses increase in summer. We performed an ecological analysis of this paradoxical seasonality in a Peruvian shantytown over 4 years. METHODS: Tuberculosis symptom-onset and diagnosis dates
Adams, Akhtar, Ane-Anyangwe, Anibarro, Arnedo-Pena, Baker, C. A. Evans, C. Jongkaewwattana, Chew, Dowling, Drucker, E. S. Ramos, Ford, G. Sandhu, J. J. Lewis, J. S. Friedland, K. Zevallos, Kennel, Liu, Lonnroth, Luquero, M. A. Tovar, M. R. Baldwin, Martineau, Nagayama, Onifade, Parrinello, R. H. Gilman, R. Montoya, Rao, Rook, S. G. Schumacher, Schaaf, Stamp, T. Wingfield, ten Asbroek, Wilkinson, Yang, Yoshiyama   +38 more
core   +2 more sources

French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025

Journal of the European Academy of Dermatology and Venereology, EarlyView.
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault, Emilie Brenaut, Marie‐Emeline Marniquet, Carla Berthault, Lea Canoen, Clarisse Marcombes, Audrey Melin, Raphaël Ouakrat, Julie Charles, Stephane Mouret, Olivier Potie, Laetitia Penso, Laura Pina Vegas, Guillaume Larid, Marine Roux, Colombe Bougeard, Sandy Sylvain, Clara Labonne, Tania Randriamiarana, Da Hee Pitaud, Floriane Etheve, Jeremy Gottlieb, Laurie Gouillon, Marine Chastagner, Emilie Sbidian, Hélène Aubert, on behalf of the Psoriasis Research Group of the French Society of Dermatology (Groupe de Recherche sur le Psoriasis de la Société Française de Dermatologie), Hélène Aubert, Marie Masson Regnault, Emilie Brenaut, Emilie Sbidian, Laura Pina Vegas, Laetitia Penso, Jeremy Gottlieb, Marine Roux, Clara Labonne, Tania Randriamiarana, Floriane Etheve, Da Hee Pitaud, Marie‐Emeline Marniquet, Carla Berthault, Clarisse Marcombes, Audrey Melin, Colombe Bougeard, Julie Charles, Olivier Potie, Léa Canoen, Laurie Gouillon, Marine Chastagner, Sandy Sylvain, Guillaume Larid, Raphaël Ouakrat   +51 more
wiley   +1 more source

Prevalence and exposure variables of latent infection by mycobacterium tuberculosis in healthcare workers [PDF]

Revista Brasileira de Enfermagem
Objectives: To identify in the scientific literature the prevalence, diagnostic methods, and exposure variables of latent infection by Mycobacterium tuberculosis in healthcare workers. Methods: An integrative review of the scientific literature based on
Raphael Sampaio dos Santos, Katerine Moraes dos Santos, Angela Maria Mendes Abreu, Cristiane Cardoso de Paula, Regina Célia Gollner Zeitoune   +4 more
doaj   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, EarlyView.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Latent tuberculosis infection in children: diagnostic approaches

European Journal of Clinical Microbiology & Infectious Diseases, 2012
Tuberculosis (TB) remains an important public health problem and a leading infectious cause of death. Diagnosis and treatment of latent tuberculosis infection (LTBI) is important for TB control and elimination. Nevertheless, the diagnosis of LTBI in both adults and children remains complex, since there is no gold standard. The development of interferon
Amanatidou, V., Syridou, G., Mavrikou, M., Tsolia, M.N.   +3 more
openaire   +3 more sources

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Re‐Examining Treatment of Latent Tuberculosis Infection

Canadian Journal of Infectious Diseases and Medical Microbiology, 2001
In April 2000, the American Thoracic Society published guidelines for targeted tuberculin testing and the treatment of latent tuberculosis infection (LTBI) (1). These guidelines are a joint statement of the American Thoracic Society and the Centers for Disease Control and Prevention, and were endorsed by both the Infectious Diseases Society of America ...
Johnston, B Lynn, Conly, John M
openaire   +4 more sources