Results 91 to 100 of about 46,620 (192)

Infection control in the brain and the eye

Acta Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Immune Response to Mycobacterial Infection: Lessons from Flow Cytometry

Clinical and Developmental Immunology, 2013
Detecting and treating active and latent tuberculosis are pivotal elements for effective infection control; yet, due to their significant inherent limitations, the diagnostic means for these two stages of tuberculosis (TB) to date remain suboptimal. This
Nikoletta Rovina, Marios Panagiotou, Konstantinos Pontikis, Magdalini Kyriakopoulou, Nikolaos G. Koulouris, Antonia Koutsoukou   +5 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, Volume 78, Issue 8, Page 959-966, August 2026.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Advances in the Diagnosis of Latent Tuberculosis Infection

Infection and Drug Resistance
Latent tuberculosis infection (LTBI) is a critical stage of tuberculosis infection in which Mycobacterium tuberculosis (MTB) is dormant and does not cause active disease. Traditionally, the most commonly used clinical methods for diagnosing LTBI have been the tuberculin skin test (TST) and the interferon-gamma release assay (IGRA).
Haiying Zhang, Weiwei Guan, Jikun Zhou
openaire   +4 more sources

Diagnostic accuracy study of STANDARD TB-Feron FIA and STANDARD TB-Feron ELISA tests for tuberculosis infection diagnosis in Eastern European setting

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Introduction: Tuberculosis infection (TBI) is diagnosed based on a positive immune response to M. tuberculosis antigens. This study aimed to evaluate both the qualitative and quantitative performance of two novel IGRA-based tests, the STANDARD E TB-Feron
Valeriu Crudu, Dumitru Chesov, Alexandru Codreanu, Nadejda Turcanu, Nelly Ciobanu, Liuba Nepoliuc, Doina Rusu   +6 more
doaj   +1 more source

Factors Associated with Pulmonary Tuberculosis and Latent Tuberculosis Infection of Household Contacts with Drug-Sensitive Tuberculosis Patients in Medan

Public Health of Indonesia
Background: Latent Tuberculosis Infection (LTBI) has the potential to develop into active TB. Therefore, appropriate diagnosis and management are essential, especially in high-risk populations such as individuals who are in household contact with active
Rina Sundari, Bintang Yinke Magdalena Sinaga, Delores Elisabeth Sormin, Arlinda Sari Wahyuni   +3 more
doaj   +1 more source

Latentna tuberkulozna infekcija

Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, 2012
Latentna tuberkulozna infekcija (LTBI) definira se kao supklinička infekcija bakterijom Mycobacterium (M.) tuberculosis. Kod djece i osoba oslabljenog imunološkog sustava, zbog pojedinih patoloških stanja ili terapijskih postupaka, postoji veći rizik za aktivaciju LTBI-ja u aktivnu tuberkulozu u odnosu na opću populaciju, te je takvu infekciju potrebno
openaire   +3 more sources

Screening for Latent Tuberculosis Infection

JAMA Network Open, 2023
openaire   +2 more sources

Use of Low Molecular Weight Antigens of Mycobacterium tuberculosis as a New Skin Test for Specific Diagnosis of Tuberculosis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: Tuberculosis (TB) is an infectious disease and about one-third of the world population are infected with latent TB infection.
Davoud Sadeghi Gariz, Nader Mosavari
doaj