Results 121 to 130 of about 53,392 (269)

Co‐Occurring Risk Factors for Tuberculosis Preventive Treatment Non‐Adherence Among People Living With HIV in Ethiopia: A Latent Class Analysis

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objective Non‐adherence to tuberculosis preventive treatment (TPT) among people living with HIV (PLHIV) is a critical issue in Ethiopia and other Sub‐Saharan African countries, where both TB and HIV burdens are high. To reduce TPT non‐adherence among PLHIV, it is crucial to identify those at risk and implement targeted interventions. Therefore,
Edao Sinba Etu   +5 more
wiley   +1 more source

Advances in the Diagnosis of Latent Tuberculosis Infection

open access: yesInfection and Drug Resistance
Latent tuberculosis infection (LTBI) is a critical stage of tuberculosis infection in which Mycobacterium tuberculosis (MTB) is dormant and does not cause active disease. Traditionally, the most commonly used clinical methods for diagnosing LTBI have been the tuberculin skin test (TST) and the interferon-gamma release assay (IGRA).
Haiying Zhang, Weiwei Guan, Jikun Zhou
openaire   +4 more sources

Efficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1494-1506, July 2026.
ABSTRACT Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded,
Nichola Cooper   +546 more
wiley   +1 more source

Immune Response to Mycobacterial Infection: Lessons from Flow Cytometry

open access: yesClinical and Developmental Immunology, 2013
Detecting and treating active and latent tuberculosis are pivotal elements for effective infection control; yet, due to their significant inherent limitations, the diagnostic means for these two stages of tuberculosis (TB) to date remain suboptimal. This
Nikoletta Rovina   +5 more
doaj   +1 more source

COVID‐19 as a Potential Trigger for Tuberculosis: Insights From a Large‐Scale Japanese Insurance Database Analysis

open access: yesJournal of General and Family Medicine, Volume 27, Issue 4, July 2026.
In a nationwide propensity score–matched cohort study using Japanese insurance claims data, prior COVID‐19 was associated with a fourfold higher risk of subsequent active tuberculosis treatment initiation. The association was particularly pronounced among individuals with prior tuberculosis history.
Daisuke Miyamori   +3 more
wiley   +1 more source

Investigação do papel da proteína codificada pelo gene Rv1419 de Mycobacterium tuberculosis durante a infecção: potencial diagnóstico e propriedades imunoregulatórias [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA tuberculose é uma doença causada pelo bacilo Mycobacterium tuberculosis que mata anualmente cerca de 2 milhões de pessoas
Nogueira, Lucas de Lima
core  

Harvest increase and culling as tools for managing chronic wasting disease in white‐tailed deer

open access: yesThe Journal of Wildlife Management, Volume 90, Issue 5, July 2026.
We used an agent‐based model to simulate the effect of CWD management on a white‐tailed deer population in northwest Indiana and northeast Illinois. Our results suggest that wildlife managers should reconsider how and if they should manage CWD. Abstract Chronic wasting disease (CWD), a transmissible spongiform encephalopathy that affects white‐tailed ...
Jonathan D. Brooks   +3 more
wiley   +1 more source

In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease

open access: yes, 2008
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Pulimood, AB   +3 more
core  

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

open access: yesThe Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song   +6 more
wiley   +1 more source

An Aging Clock Based on Immune Repertoire Features: COVID‐19 Accelerates Aging

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
We systematically profiled TCR/BCR repertoires in Chinese individuals and paired COVID‐19 samples, revealed aging‐driven remodeling and COVID‐accelerated immune senescence, and built a reliable immune repertoire aging clock for immune senescence evaluation.
Xin Gao   +13 more
wiley   +1 more source

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